{"id":31,"date":"2015-12-14T18:56:03","date_gmt":"2015-12-14T18:56:03","guid":{"rendered":"http:\/\/elements.chem.umass.edu\/knappgroup\/?page_id=31"},"modified":"2020-01-15T19:54:50","modified_gmt":"2020-01-15T19:54:50","slug":"members","status":"publish","type":"page","link":"https:\/\/elements.chem.umass.edu\/knappgroup\/members\/","title":{"rendered":"Members"},"content":{"rendered":"

Principal Investigator<\/p>\n

\n

\"\"<\/p>\n

Prof. Michael J. Knapp<\/div>\n
B.S. Biochemistry and Cell Biology, UC San Diego<\/div>\n
PhD Chemistry, UC San Diego<\/div>\n
NIH Postdoctoral Fellow, UC Berkeley<\/div>\n
mknapp@chem.umass.edu<\/a><\/div>\n
LinkedIn<\/a><\/div>\n
CV<\/a><\/div>\n
Associate Professor of Chemistry, with research interests in hypoxia sensing, SERS, and oxidation chemistry. He leads a multidisciplinary group working to manipulate the hypoxia response by activating or inhibiting the HIF hydroxylases, and develop new sensors with surface-enhanced Raman.<\/div>\n<\/div>\n
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Group Members<\/p>\n

Dr. Philip Shivokevich, Visiting Assistant Professor<\/p>\n

LinkedIn<\/a><\/p>\n

Michael Mingroni<\/p>\n

LinkedIn<\/a><\/p>\n

\u00a0<\/p>\n

Isabella Jaen-Maisonet<\/p>\n

Owen Kuklinski<\/p>\n

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Alumni<\/p>\n

Ran Duan<\/strong><\/p>\n<\/div>\n<\/div>\n

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\"\"<\/p>\n

Dr. Vanessa Chaplin<\/div>\n
B.S. Forensic Science and Biology, Bay Path College (2012)<\/div>\n
Ph.D. Chemistry (2018)<\/div>\n
vchaplin@chem.umass.edu<\/a><\/div>\n
“Role of the Facial Triad in Factor Inhibiting HIF-1\u03b1 (FIH): Ligand Binding, Substrate Selectivity, and Coupling”<\/div>\n
LinkedIn<\/a><\/div>\n
\u00a0<\/div>\n
Nayana Thimmiah<\/strong><\/div>\n
B.S. Biochemistry (2018) Honors Thesis: “Utilizing alternate substrates of Factor Inhibiting Hypoxia Inducible Factor-1\u03b1 (FIH) to analyze enzyme reactivity”<\/em><\/div>\n<\/div>\n
\u00a0<\/div>\n
\n

\"\"<\/p>\n

Alex Barbato<\/div>\n
B.S. Chemistry (2017)<\/div>\n
Honors Thesis:<\/div>\n
“An Alternate Substrate of Factor Inhibiting HIF-1\u03b1 (FIH) for Bioorthogonal Labeling of Proteins”<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"\"<\/p>\n

Michael McKeon<\/div>\n
B.S. Chemical Engineering (2017)<\/div>\n
Honors Thesis:<\/div>\n
“Engineering Alternate Radical Rebound in Factor Inhibiting\u00a0 through Random Site Saturated Mutagenesis”<\/div>\n
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\u00a0<\/div>\n<\/div>\n
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\"\"<\/p>\n

Dr. Cristina Martin<\/strong><\/div>\n
Ph.D. Chemistry (2015) <\/em>“Kinetic and Dynamic Insights into the Substrate Interactions and Catalysis of Factor Inhibiting HIF-1 (FIH-1)”<\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n
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\"\"<\/p>\n

Alex Eisenbeis<\/div>\n
B.S. Keene State<\/div>\n
M.S. Adv. Molecular Biology (2015)<\/div>\n
“Cell penetrating fusions for delivery of FIH”<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Cornelius\"<\/p>\n

Dr. Cornelius Taabazuing<\/div>\n
B.S. Biochemistry and Molecular Biology, UMass Amherst<\/div>\n
Destination: New York<\/div>\n
Ph.D. Chemistry (2014) \u201cInhibition and Cofactor Targeting of Hypoxia-Sensing Enzymes\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"JohnH\"<\/p>\n

Dr. John Hangasky<\/div>\n
B.S. Forensic Science, University of New Haven<\/div>\n
Destination: UC Berkeley<\/div>\n
Ph.D. Chemistry (2014) \u201cFactor Inhibiting HIF\u2019s (FIH) structure controls O2 activation and reactivity\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Serap\"<\/p>\n

Dr. Serap Pektas<\/div>\n
B.S. Chemistry, Cumhuriyet \u00dcniversity<\/div>\n
Destination: Faculty of RTEU, Recep Tayyip Erdogan University<\/a><\/div>\n
Ph.D. Chemistry (2013) \u201cO2 activation and allosteric Zn(II) binding on HIF-prolyl hydroxylase-2 (PHD2)\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Shannon\"<\/p>\n

Dr. Shannon Coates-Flagg<\/div>\n
B.S. Biochemistry (2005), UNLV<\/div>\n
\n
Current: Sr Scientist\/Manager & Analytical Team Lead<\/div>\n
Bristol-Myers Squibb<\/span><\/div>\n<\/div>\n
Ph.D. Chemistry (2011) \u201cSelective inhibition and mechanistic studies of the human O2 sensor, prolyl hydroxylase domain 2 (PHD2)\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Evren\"<\/p>\n

Dr. Evren Saban<\/div>\n
B.S. (2005), Bogazici University, Istanbul<\/div>\n
Destination: TUBITAK MRC Institute of Chemical Technologies<\/div>\n
Ph.D. (2011) \u201cControlled oxygen activation in human oxygen sensor FIH\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Breanne\"<\/p>\n

Breanne Holmes<\/div>\n
B.S. Chemistry (2008), University of Rochester<\/div>\n
Destination: Environmental Sciences & Engineering, UNC Chapel Hill<\/div>\n
M.S. Chemistry (2011) \u201cSelective Inhibition Studies of Factor Inhibiting HIF (FIH)\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
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\"Yuan-Han\"<\/p>\n

Dr. Yuan-Han (Robert) Chen<\/div>\n
Destination: University of Buffalo<\/div>\n
Ph.D. MCB (2009) \u201cThe active site chemistry of factor inhibiting HIF-1, coordination, bonding, and reaction\u201d<\/div>\n<\/div>\n
\n

\"Adrienne\"<\/p>\n

Dr. Adrienne Gilbert<\/div>\n
B.S. Chemistry (2003) Purdue<\/div>\n
Current: Indiana State University<\/a><\/div>\n
Ph.D. Chemistry (2009) \u201cIntermolecular electron transfer reactivity and dynamics of cytochrome c \u2013 nanoparticle adducts\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"MeaghanG\"<\/p>\n

Dr. Meaghan Germain<\/div>\n
B.A. Chemistry (2003) Saint Anselm College<\/div>\n
Destination: Tufts University<\/div>\n
Ph.D. Chemistry (2008) \u201cDetection of chemical explosives with Zn(Salicylaldimine) complexes: mechanism and applications\u201d<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Halil\"<\/p>\n

Dr. Halil Bayraktar<\/div>\n
B.S. Bogazici University, Istanbul<\/div>\n
Destination: Harvard University<\/div>\n
Ph.D. Chemistry (2008) \u201cInterface of protein-nanoparticle hybrid structures and self-assembly of nanoparticles\u201d<\/div>\n
Bayraktar Lab<\/a><\/div>\n
Tabwalk<\/a><\/div>\n<\/div>\n
\n

\"MeaghanV\"<\/p>\n

Meaghan Valliere<\/div>\n
B.S. Chemistry (2014) Honors Thesis<\/div>\n
Destination: UCLA Biochemistry<\/div>\n
Website<\/a><\/div>\n<\/div>\n
\n

\"Tyler\"<\/p>\n

Tyler O\u2019Neil<\/div>\n
B.S. Biology (2013) Honors Thesis: \u201cSubstrate Triggering of HIF-Prolyl Hydroxylase Connects Substrate Binding to Catalysis\u201d<\/div>\n
Destination: St. George\u2019s University Medical<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Kate_liedell\"<\/p>\n

Kate Liedell<\/div>\n
B.S. Chemistry (2013) Honors Thesis: \u201cWater Exchange Kinetics in Factor Inhibiting Hypoxia Inducing Factor\u201d<\/div>\n
Destination: UMass School of Education; Needham High<\/div>\n<\/div>\n
\n

\"Geoff\"<\/p>\n

Geoff Ivison<\/div>\n
B.A. Biochemistry of Human Health, Hampshire College (2012) Division III project \u201cInvestigating the Mechanism of an Intracellular Oxygen Sensing Enzyme\u201d<\/div>\n
Destination: Biocurious; Stanford Immunology<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Jaqueline\"<\/p>\n

Jaqueline Dorhout<\/div>\n
B.S. Chemistry (2012) Honors Thesis: \u201cSynthesis of Potential Inhibitors of FIH Fe2+ Active Site\u201d<\/div>\n
Destination: Los Alamos National Lab, UNLV Radiochemistry<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"Lindsay\"<\/p>\n

Lindsay Comeaux Schnarr<\/div>\n
B.S. Chemistry, UC Santa Cruz<\/div>\n
Destination: Master of Architecture Program at UMass Amherst; Architectural Designer at Steffian Bradley Architects<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
\n

\"TomV\"<\/p>\n

Tom Vargo<\/div>\n
B.S. Chemistry (2006) Honors Thesis<\/div>\n
Destination: University of Pittsburgh Senior Scientist at AbbVie<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n
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\"\"<\/p>\n

Todd Ratazcjak<\/div>\n
B.S. Chemistry (2006) Honors Thesis<\/div>\n
Destination: UNC Chapel Hill; Senior Analytical Engineer at Yokogawa<\/div>\n
LinkedIn<\/a><\/div>\n<\/div>\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Principal Investigator Prof. Michael J. Knapp B.S. Biochemistry and Cell Biology, UC San Diego PhD Chemistry, UC San Diego NIH Postdoctoral Fellow, UC Berkeley mknapp@chem.umass.edu LinkedIn CV Associate Professor of Chemistry, with research interests in hypoxia sensing, SERS, and oxidation chemistry. He leads a multidisciplinary group working to manipulate the hypoxia response by activating or […]<\/p>\n","protected":false},"author":44,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-31","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages\/31","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/users\/44"}],"replies":[{"embeddable":true,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/comments?post=31"}],"version-history":[{"count":39,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages\/31\/revisions"}],"predecessor-version":[{"id":536,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages\/31\/revisions\/536"}],"wp:attachment":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/media?parent=31"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}