{"id":33,"date":"2015-12-14T18:56:08","date_gmt":"2015-12-14T18:56:08","guid":{"rendered":"http:\/\/elements.chem.umass.edu\/knappgroup\/?page_id=33"},"modified":"2019-07-27T19:29:44","modified_gmt":"2019-07-27T19:29:44","slug":"publications","status":"publish","type":"page","link":"https:\/\/elements.chem.umass.edu\/knappgroup\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

(52)\u00a0\u00a0\u00a0\u00a0 Chaplin VD, Hangasky JA, Huang HT, Duan R, Maroney MJ, Knapp MJ. \u201cChloride Supports O2<\/sub> Activation in the D201G Facial Triad Variant of Factor-Inhibiting Hypoxia Inducible Factor, an \u03b1-Ketoglutarate Dependent Oxygenase.\u201d Inorg. Chem.<\/em> (2018) 57<\/strong>:12588\u201312595<\/a> doi: 10.1021\/acs.inorgchem.8b01736.<\/p>\n

(51)\u00a0\u00a0\u00a0\u00a0 Iyer SR, Chaplin VD, Knapp MJ, Solomon EI.\u201d O2<\/sub> Activation by Nonheme FeII \u03b1-Ketoglutarate-Dependent Enzyme Variants: Elucidating the Role of the Facial Triad Carboxylate in FIH.\u201d J. Amer. Chem. Soc.<\/em> (2018) 140<\/strong>:11777-11783<\/a>. doi: 10.1021\/jacs.8b07277<\/p>\n

(50)\u00a0\u00a0\u00a0\u00a0 Chaplin VD, Valliere MA, Hangasky JA, Knapp MJ \u201cInvestigations on the role of a solvent tunnel in the \u03b1-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).\u201d J Inorg Biochem.<\/em> (2018) 178<\/strong>:63-69<\/a>. 10.1016\/j.jinorgbio.2017.10.001.<\/p>\n

(49)\u00a0\u00a0\u00a0\u00a0 VD Chaplin, AN Barbato, MJ Knapp,* 2017.\u00a0 \u201cMammalian O2<\/sub> Sensing and Signaling,\u201d Chapter 7 in Gas Sensing in Cells<\/em>, RSC publishers, S. Aono, Ed. (2017) DOI 10.1039\/9781788012836-00219<\/a>.<\/p>\n

(48)\u00a0\u00a0\u00a0\u00a0 JA Hangasky, CY Taabazuing, CB Martin, SJ Eron, SC Garman, MJ Knapp* “The facial triad in the alpha-ketoglutarate oxygenase FIH: a role for sterics in linking substrate binding to O2 activation” J. Inorg. Biochem,<\/em> 166<\/strong>(2017):26-33. https:\/\/doi.org\/10.1016\/j.jinorgbio.2016.10.007<\/a><\/p>\n

(47)\u00a0\u00a0\u00a0\u00a0 Taabazuing, CY; Fermann, J; Garman, S; Knapp, MJ.* “Substrate promotes productive gas binding in the \u03b1KG-dependent oxygenase FIH” Biochemistry<\/em>, (2016) 55(2):277-86. https:\/\/doi.org\/10.1021\/acs.biochem.5b01003<\/a><\/p>\n

(46)\u00a0\u00a0\u00a0\u00a0 Pektas S, Taabazuing CY, Knapp MJ.* \u201cIncreased Turnover at Limiting O2 Concentrations by the Thr(387) \u2192 Ala Variant of HIF-Prolyl Hydroxylase PHD2.\u201d Biochemistry<\/em> (2015) 54(18):2851-7. https:\/\/doi.org\/10.1021\/bi501540c<\/a><\/p>\n

(45) Hangasky, J. A.; Gandhi, H.; Valliere, M. A.; Ostrom, N. E.; Knapp, M. J. \u201cThe Rate-Limiting Step of O2 activation in the a-Ketoglutarate Oxygenase Factor Inhibiting Hypoxia Inducible Factor,\u201c Biochemistry,<\/em> 2014, 53, pp 8077\u20138084<\/strong><\/a><\/p>\n

(44) Hangasky, J. A.; Ivison, G. T.; Knapp, M. J. \u201cSubstrate Positioning by Gln239 Stimulates Turnover in Factor Inhbiting HIF, an aKG-dependent hydroxylase,\u201c Biochemistry<\/em>, 2014, 53, pp 5750\u20135758<\/strong><\/a><\/p>\n

(43) Taabazuing, C. Y.; Hangasky, J. A.; Knapp, M. J. \u201cOxygen Sensing Strategies in Mammals and Bacteria,\u201c J. Inorg. Biochem.<\/em> 2014, 133, pp 63\u201372<\/strong><\/a><\/p>\n

(42) Light, K. M.; Hangasky, J. A.; Knapp, M. J.; Solomon, E. I. \u201cFirst- and second-sphere contributions to Fe(II) site activation by cosubstrate binding in non-heme Fe enzymes,\u201c Dalton Trans.<\/em>, 2014, 43, pp 1505\u20131508<\/strong><\/a><\/p>\n

(41) Pektas, S.; Knapp, M. J. \u201cSubstrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change,\u201c J. Inorg. Biochem.<\/em>, 2013, 126, pp 55\u201360<\/strong><\/a><\/p>\n

(40) Light, K. M.; Hangasky, J. A.; Knapp, M. J.; Solomon, E. I. \u201cSpectroscopic Studies of the Mononuclear Nonheme Fell Enzyme FIH: Second-Sphere Contributions to Reactivity,\u201c J. Amer. Chem. Soc.<\/em>, 2013, 135 (26), pp 9665\u20139674<\/strong><\/a><\/p>\n

(39) Hangasky, J. A.; Taabazuing, C. Y.; Valliere, M. A.; Knapp, M. J. \u201cImposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the alpha KG dependent oxygenases ,\u201c Metallomics<\/em>, 2013, 5 (4), pp 287\u2013301<\/strong><\/a><\/p>\n

(38) Hangasky, J. A.; Saban, E.; Knapp, M. J. \u201cInverse Solvent Isotope Effects Arising from Substrate Triggering in the Factor Inhibiting Hypoxia Inducible Factor,\u201c Biochemistry<\/em>, 2013, 52 (9), pp 1594\u20131602<\/strong><\/a><\/p>\n

(37) Flagg, S. C.; Giri, N.; Pektas, S.; Maroney, M. J.; Knapp, M. J. \u201cInverse Solvent Isotope Effects Demonstrate Slow Aquo Release from Hypoxia Inducible Factor-Prolyl Hydroxylase (PHD2),\u201c Biochemistry<\/em>, 2012, 51 (33), pp 6654\u20136666<\/strong><\/a><\/p>\n

(36) Flagg, S. C.; Martin, C. B.; Taabazuing, C. Y.; Knapp, M. J. \u201cScreening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH),\u201c J. Inorg. Biochem.<\/em>, 2012, 113, pp 25\u201330<\/strong><\/a><\/p>\n

(35) Saban, E.; Chen, Y.-H.; Hangasky, J. A.; Taabazuing, C. Y.; Holmes, B. E.; Knapp, M. J. \u201cThe Second Coordination Sphere of FIH Controls Hydroxylation,\u201c Biochemistry<\/em>, 2011, 50 (21), pp 4733\u20134740<\/strong><\/a><\/p>\n

(34) Saban, E.; Flagg, S. C.; Knapp, M. J. \u201cUncoupled O-2 activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species,\u201c J. Inorg. Biochem.<\/em> 2011, 105 (5), pp 630\u2013636<\/strong><\/a><\/p>\n

(33) Meaghan E. Germain, Michael J. Knapp. \u201cOptical explosives detection: from color changes to fluorescence turn-on,\u201c Chem. Soc. Rev.<\/em>, 2009, 38 (9), pp 2543\u20132555<\/strong><\/a><\/p>\n

(32) Carver, A. C.; De, M.; Bayraktar, H.; Rana, S.; Rotello, V. M.; Knapp, M. J.* \u201cIntermolecular Electron-Transfer Catalyzed on Nanoparticle Surfaces,\u201c J. Am. Chem. Soc.<\/em>, 2009, 131 (11), pp 3798\u20133799<\/strong><\/a><\/p>\n

(31) Carver, A. C.; Knapp, M. J.* “Electron and energy transfer reactions of [Ru(bpy)3]2+*\/3+ with copper-phenolates,” Polyhedron<\/em> 2008, 27, 3313<\/strong><\/a><\/p>\n

(30) Chen, Y.-H.; Comeaux, L. M.; Herbst, R. M.; Saban, E.; Kennedy, D. C.; Maroney, M. J.; Knapp, M. J.* “Coordination changes and auto-hydroxylation of FIH-1: uncoupled O2-activation in a human hypoxia sensor,” J. Inorg. Biochem. 2008, accepted for a special \u201cYoung Investigators Issue.\u201d J. Inorg. Biochem.<\/em>Volume 102, Issue 12, December 2008, 2120-2129<\/strong><\/a><\/p>\n

(29) Germain, M. E.; Knapp, M. J.* “Turn-on fluorescence detection of H2O2 and TATP,” Inorg. Chem.<\/em>, 2008, 47 (21), pp 9748\u20139750.<\/strong><\/a><\/p>\n

(28) Germain, M. E.; Vargo, T. R.; McClure, B. A.; Rack, J. J.; Van Patten, P. G.; Odoi, M.; Knapp, M. J.* “Quenching Mechanism of Zn(Salicylaldimine) by Nitroaromatics,” Inorg. Chem.<\/em> 2008, 47, 6203-6211.<\/strong><\/a><\/p>\n

(27) Germain, M. E.; Knapp,* M. J. \u201cDiscrimination of nitroaromatics and explosives mimics by a fluorescent Zn(salicylaldimine) sensor array\u201d, J. Am. Chem. Soc.<\/em> 2008 130 (16), 5422<\/strong><\/a><\/p>\n

(26) Chen, Y.-H.; Comeaux, L. M.; Eyles, S. J.; Knapp, M. J. “Auto-hydroxylation of FIH-1, an Fe(II), \u03b1-ketoglutarate dependent human hypoxia sensor,” Chem. Commun.<\/em> 2008<\/strong><\/a><\/p>\n

(25) Bayraktar, H, Srivastava, S.; You, C.-C.; Rotello,* V. M.; Knapp,* M. J. \u201cControlled nanoparticle assembly through protein conformational changes,\u201d Soft Matter<\/a><\/em> 2008 4, 751-756<\/a> (cover article)<\/a><\/strong>
\n\"softmatter_cover\"<\/p>\n

(24) Bayraktar, H.; You, C.-C.; Rotello, V. M.; Knapp, M. J. “Facial Control of Nanoparticle Binding to Cytochrome c” J. Am. Chem. Soc.<\/em>, 2007, 129, 2732-2733.<\/strong><\/a><\/p>\n

(23) Meaghan E. Germain, Thomas R. Vargo, Peter G. Khalifah and Michael J. Knapp, \u201cFluorescent detection of nitroaromatics and 2,3-dimethyl 2,3-dinitrobutane (DMNB) by a zinc complex: (L)Zn\u201d Inorg. Chem.<\/em>, 2007, 46, 4422-4429.<\/strong><\/a><\/p>\n

(22) Britto S. Sandanaraj, Halil Bayraktar, Kothandam Krishnamoorthy, Michael J. Knapp and Sankaran Thayumanavan, \u201cRecognition and Modulation of Cytochrome c’s Redox Properties by an Amphiphilic Homopolymer\u201d Langmuir<\/em>, 2007, 23, 3891-3897.<\/strong><\/a><\/p>\n

(21) You, C.-C.; Agasti,S. S.; De, M.; Knapp, M. J.; Rotello, V. M.; “Modulation of the Catalytic Behavior of a-Chymotrypsin at Monolayer-Protected Nanoparticle Surfaces,” J. Am. Chem. Soc.<\/em>, 2006, 128, 14612-14618.<\/strong><\/a><\/p>\n

(20) Bayraktar, H.; Ghosh, P. S.; Rotello, V. M.; Knapp, M. J. “Disruption of protein-protein interactions using nanoparticles: inhibition of cytochrome c peroxidase,” Chem. Comm.<\/em> 2006, 13, 1390-1392.<\/strong><\/a><\/p>\n

(19) Knapp, M. J.; Meyer, M. M.; Klinman, J. P. In Handbook of Hydrogen Transfer, Vol; 2: Biological Aspects of Hydrogen Transfer; Schowen, R. L., Klinman, J. P., Eds.; Wiley VCH: Weinheim<\/em>, 2006.<\/strong><\/p>\n

(18) Knapp, M. J.; Klinman, J. P. “Kinetic studies of oxygen reactivity in soybean lipoxygenase-1,” Biochemistry<\/em> 2003, 42, 11466-11475.<\/strong><\/p>\n

(17) Sanudo, E. C.; Grillo, V. A.; Knapp, M. J.; Bollinger, J. C.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Tetranuclear manganese complexes with dimer-of-dimer and ladder structures from the use of a bis-bipyridyl ligand,” Inorg. Chem.<\/em> 2002, 41, 2441-2450.<\/strong><\/p>\n

(16) Francisco, W. A.; Knapp, M. J.; Blackburn, N. J.; Klinman, J. P. “Hydrogen tunneling in peptidylglycine alpha-hydroxylating monooxygenase,” J. Am. Chem. Soc.<\/em> 2002, 124, 8194-8195.<\/strong><\/p>\n

(15) Knapp, M. J.; Klinman, J. P. “Environmentally coupled hydrogen tunneling – Linking catalysis to dynamics,” Eur. J. Biochem.<\/em> 2002, 269, 3113-3121.<\/strong><\/p>\n

(14) Knapp, M. J.; Rickert, K.; Klinman, J. P. “Temperature-dependent isotope effects in soybean lipoxygenase-1: Correlating hydrogen tunneling with protein dynamics,” J. Am. Chem. Soc.<\/em> 2002, 124, 3865-3874.<\/strong><\/p>\n

(13) Knapp, M. J.; Seebeck, F. P.; Klinman, J. P. “Steric control of oxygenation regiochemistry in soybean lipoxygenase-1,” J. Am. Chem. Soc.<\/em> 2001, 123, 2931-2932.<\/strong><\/p>\n

(12) Krzystek, J.; Telser, J.; Knapp, M. J.; Hendrickson, D. N.; Aromi, G.; Christou, G.; Angerhofer, A.; Brunel, L. C. “High-frequency and -field electron paramagnetic resonance of high-spin manganese(III) in axially symmetric coordination complexes,” Appl. Magn. Reson.<\/em> 2001, 21, 571-585.<\/strong><\/p>\n

(11) Maes, E. M.; Knapp, H. J.; Czernuszewicz, R. S.; Hendrickson, D. N. “Ligand conformational effects on the resonance Raman signature of [Fe4S4(SAryl)4]2- clusters,” J. Phys. Chem.<\/em> B 2000, 104, 10878-10884.<\/strong><\/p>\n

(10) Knapp, M. J.; Krzystek, J.; Brunel, L. C.; Hendrickson, D. N. “High-frequency EPR study of the ferrous ion in the reduced rubredoxin model [Fe(SPh)4]2-,” Inorg. Chem.<\/em> 2000, 39, 281-288.<\/strong><\/p>\n

(9) Brechin, E. K.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “New hexanuclear and octanuclear iron(III) oxide clusters: octahedral [Fe6O2]14+ species and core isomerism in [Fe8O4]16+ complexes,” Inorg. Chim. Acta<\/em> 2000, 297, 389-399.<\/strong><\/p>\n

(8) Aromi, G.; Knapp, M. J.; Claude, J. P.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “High-spin molecules: Hexanuclear Mn-III clusters with [Mn6O4X4]6+ (X = Cl-, Br-) face-capped octahedral cores and S=12 ground states,” J. Am. Chem. Soc.<\/em> 1999, 121, 5489-5499.<\/strong><\/p>\n

(7) Knapp, M. J.; Krzystek, J.; Brunel, L. C.; Hendrickson, D. N. “High-field EPR study of resonance-delocalized [Fe2(OH)3(tmtacn)2]2+,” Inorg. Chem.<\/em> 1999, 38, 3321-3328.<\/strong><\/p>\n

(6) Grant, C. M.; Stamper, B. J.; Knapp, M. J.; Folting, K.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Syntheses, crystal structures and properties of mononuclear chromium(III) and dinuclear vanadium(III) and copper(II) complexes with a bis-bipyridyl ligand,” J. Chem. Soc. Dalton<\/em> 1999, 3399-3405.<\/strong><\/p>\n

(5) Grant, C. M.; Knapp, M. J.; Streib, W. E.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Dinuclear and hexanuclear iron(III) oxide complexes with a bis(bipyridine) ligand: A new [Fe6(m3-O)4]10+ core,” Inorg. Chem.<\/em> 1998, 37, 6065-6070.<\/strong><\/p>\n

(4) Seela, J. L.; Knapp, M. J.; Kolack, K. S.; Chang, H. R.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Structural and magnetochemical properties of mono-, di-, and trinuclear Manganese(III) dithiolate complexes,” Inorg. Chem.<\/em> 1998, 37, 516-525.<\/strong><\/p>\n

(3) Grant, C. M.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “A new structural type in iron carboxylate cluster chemistry via use of bis-bipyridine ligands: [Fe6O4Cl4(O2CPh)4L-2][FeCl4]2,” Chem. Comm.<\/em> 1998, 1753-1754.<\/strong><\/p>\n

(2) Aromi, G.; Claude, J. P.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “High-spin molecules: Hexanuclear [Mn6O4Cl4(Me2dbm)6] (Me2dbmH = 4,4 ‘-dimethyldibenzoylmethane) with a near tetrahedral [Mn6O4Cl4]6+ core and a S=12 ground state,” J. Am. Chem. Soc.<\/em> 1998, 120, 2977-2978.<\/strong><\/p>\n

(1) Grillo, V. A.; Knapp, M. J.; Bollinger, J. C.; Hendrickson, D. N.; Christou, G. “Bis(bipyridine) ligands in manganese carboxylate cluster chemistry: Self-assembly of a cluster complex with two butterfly-like [Mn4(m3-O)2]8+ cores,” Angew. Chem. Int. Ed.<\/em> 1996, 35, 1818-1820.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

(52)\u00a0\u00a0\u00a0\u00a0 Chaplin VD, Hangasky JA, Huang HT, Duan R, Maroney MJ, Knapp MJ. \u201cChloride Supports O2 Activation in the D201G Facial Triad Variant of Factor-Inhibiting Hypoxia Inducible Factor, an \u03b1-Ketoglutarate Dependent Oxygenase.\u201d Inorg. Chem. (2018) 57:12588\u201312595 doi: 10.1021\/acs.inorgchem.8b01736. (51)\u00a0\u00a0\u00a0\u00a0 Iyer SR, Chaplin VD, Knapp MJ, Solomon EI.\u201d O2 Activation by Nonheme FeII \u03b1-Ketoglutarate-Dependent Enzyme Variants: […]<\/p>\n","protected":false},"author":44,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-33","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages\/33","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/users\/44"}],"replies":[{"embeddable":true,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/comments?post=33"}],"version-history":[{"count":6,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages\/33\/revisions"}],"predecessor-version":[{"id":496,"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/pages\/33\/revisions\/496"}],"wp:attachment":[{"href":"https:\/\/elements.chem.umass.edu\/knappgroup\/wp-json\/wp\/v2\/media?parent=33"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}