{"id":265,"date":"2013-03-28T09:54:38","date_gmt":"2013-03-28T14:54:38","guid":{"rendered":"https:\/\/elements.chem.umass.edu\/thaigroup\/?page_id=265"},"modified":"2018-10-12T12:41:24","modified_gmt":"2018-10-12T17:41:24","slug":"responsive-asseblies","status":"publish","type":"page","link":"https:\/\/elements.chem.umass.edu\/thaigroup\/publications\/responsive-asseblies\/","title":{"rendered":"Responsive Assemblies and Materials"},"content":{"rendered":"
282)<\/a>

Wu, P.; Prachyathipsakul, T.;<\/span> Huynh, <\/span>U.;<\/span> Qiu, J.; Jerry, D. J. and Thayumanavan, S. “Optimizing Conjugation Chemistry, Antibody Conjugation Site, and Surface Density in Antibody\u2013Nanogel Conjugates (ANCs) for Cell-Specific Drug Delivery”<\/span>\u00a0<\/span>Bioconjugate Chem. <\/i>2023<\/span>, 34<\/span>, 4<\/span>, 707-718,<\/span><\/span><\/a> (DOI:10.1021\/acs.bioconjchem.3c00034)<\/span><\/p>\n

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281)<\/a>

Wang, X.; Krishna, J.; Fernandez, A.; <\/span><\/span>Thayumanavan, S<\/span>. and Abbott, N.L. <\/span>\u201cOptical Fingerprinting of Dynamic Interfacial Reaction Pathways Using Liquid Crystals<\/span>\u201d <\/span>Langmuir<\/em> 2023, 39, 1793\u22121803,<\/a> (DOI:10.1021\/acs.langmuir.2c02622)\"\"<\/span><\/p>\n<\/div><\/div>

280)<\/a>

Huynh, U.; Wu, P.; Qiu, J.; Prachyathipsakul, T.; Singh, K.; Jerry, D.J.; Gao, J. and <\/span><\/span>Thayumanavan, S<\/span>. \u201cTargeted Drug Delivery Using a Plug-to-Direct Antibody\u2013Nanogel Conjugate\u201d<\/span><\/span> Biomacromolecules<\/em> 2023, 24, 849\u2212857,<\/a> (DOI:10.1021\/acs.biomac.2c01269)\"\"<\/p>\n<\/div><\/div>

279)<\/a>

Fernandez, A.; Krishna, J.; Anson, F.; Dinsmore, A.D. and <\/span><\/span>Thayumanavan, S<\/span>. <\/span>\u201cConsequences of Noncovalent Interfacial Contacts between Nanoparticles and Giant Vesicles<\/span>\u201d <\/span>Angew. Chem.Int. Ed. <\/em>2022,61, e2022086,<\/a> (DOI:10.1002\/anie.202208616)<\/span><\/p>\n

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278)<\/a>

Agrohia D.K.; Wu, P.; Huynh, U.; Thayumanavan, S. and Vachet, R.W. <\/span>\u201cMultiplexed Analysis of the Cellular Uptake of Polymeric Nanocarriers<\/span>\u201d <\/span>Anal. Chem. 2022, 94, 22, 7901\u20137908,<\/a> (DOI:10.1021\/acs.analchem.2c00648)<\/p>\n

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277)<\/a>

Kanjilal, P.; Dutta, K.; Thayumanavan, S. \u201cThiol-Disulfide Exchange as a Route for Endosomal Escape of Polymeric Nanoparticles\u201d <\/span>Angew. Chem.Int. Ed.2022,61, e2022092<\/span><\/i>,<\/span><\/a>\u00a0 (DOI:10.1002\/anie.202209227)<\/span><\/p>\n

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276)<\/a>

Dutta, R.; Makhaik, S.; Zhao, P.; Cruz, K.G.; Park, KW; Liu, H.; Andrew, T.L.; Hardy, J.A.; Thayumanavan, S. \u201cColorimetric Cotton Swab for Viral Protease Detection\u201d Anal. Chem.<\/i><\/span>\u00a02022<\/span>, 94<\/span>, 37<\/span>, 12699\u201312705<\/span><\/a>,<\/span>\u00a0In press. (DOI:10.1021\/acs.analchem.2c02033)<\/span><\/p>\n

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268)<\/a>

Gao, J.*; Prachyathipsakul, T.*; Thayumanavan, S. \u201cMultichannel Dual Protein Sensing Using Amphiphilic Supramolecular Assemblies\u201d Chem. Commun., <\/em>2021<\/strong>, 57, 12828-12831<\/a>. (DOI:10.1039\/D1CC05407D)
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266)<\/a>

Lionello, C.; Gardin, A.; Cardellini, A.; Bochicchio, D.; Shivrayan, M.; Fernandez, A.; Thayumanavan, S.; and Pavan, G.M. \u201cToward Chemotactic Supramolecular Nanoparticles: From Autonomous Surface Motion Following Specific Chemical Gradients to Multivalency-Controlled Disassembly\u201d ACS Nano, <\/em>2021<\/strong>, 15<\/em>, 10, 16149-16161 <\/a>. (DOI:10.1021\/acsnano.1c05000)
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264)<\/a>

Liu, H.; Westley, J.; Thayumanavan, S. \u201cExcimer-monomer fluorescence changes by supramolecular disassembly for protein sensing and quantification\u201d Chem. Commun., <\/em>2021<\/strong>, 57, 9776-9779<\/a>. (DOI:10.1039\/D1CC03944J)
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263)<\/a>

Cao, R.; Gao, J.; Thayumanavan, S.; Dinsmore, A.D. \u201cTriggered interactions between nanoparticles and lipid membranes: design principles for gel formation or disruption-and-release\u201d Soft Matter, <\/em>2021<\/strong>, 17, 7069-7075<\/a>. (DOI:10.1039\/D1SM00864A)
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262)<\/a>

Anson, F.; Thayumanavan, S.; Hardy, J.A. \u201cExogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes\u201d JACS Au, <\/em>2021<\/strong>,1<\/span>, 8<\/span>, 1240\u20131256<\/span>\u00a0<\/a>. (DOI:10.1021\/jacsau.1c00261)
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254)<\/a>

Liu, B.; Thayumanavan, S. \u201cMechanistic Investigations on the Oxidative Degradation of ROS Responsive Thio-Acetal\/-Ketal Moieties and Their Implications” Cell Rep. Phys. Sci., <\/em>2020<\/strong>,1, <\/em>100271<\/a>. (DOI:10.1016\/j.xcrp.2020.100271)
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249)<\/a>

Kumar, V.; Munkhbat, O.; Secinti, H.; Thayumanavan, S \u201cDisassembly of Polymeric Nanoparticles with Enzyme-Triggered Polymer Unzipping: Polyelectrolyte Complexes vs. Amphiphilic Nanoassemblies” Chem. Commun., <\/em>2020<\/strong>, 56, <\/em>8456-8459\u00a0<\/a>. (DOI: 10.1039\/D0CC03257C)
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248)<\/a>

Kumar, V.; Koyasseril-Yehiya, T. M.; Thayumanavan, S. \u201cEnzyme-Triggered Nanomaterials and Their Applications” Molecular Assemblies: Characterization and Applications (ACS Symposium Series Ed. R. Nagarajan) <\/em>2020<\/strong>, 1355, <\/em>95-107\u00a0<\/a>. (DOI:10.1021\/bk-2020-1355.ch007 )
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246)<\/a>

Zhuang, J. and Thayumanavan, S. “Triblock\u2013Diblock Composite Nanoassemblies with Sequentially Addressable Host\u2013Guest Properties for Hydrophobics and Hydrophilics” ACS Macro Lett, <\/em>2020<\/strong>, 9, <\/em>1019-1023\u00a0<\/a>. (DOI: 10.1021\/acsmacrolett.0c00290)
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245)<\/a>

Addy, P.; Shivrayan, M.; Cencer, M.; Zhuang, J.; Moore, J.; Thayumanavan, S. “A Polymer with Competing Depolymerization Pathways: Chain Unzipping vs. Chain Scission” ACS Macro Lett, <\/em>2020,<\/strong> 9, <\/em>855\u2013859\u00a0<\/a>. (DOI: 10.1021\/acsmacrolett.0c00250)
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243)<\/a>

Fernandez, A.; Zentner, C.; Shivrayan, M.; Samson, E.; Savagatrup, S.; Zhuang, J.; Swager, T.M.; Thayumanavan, S. “Programmable Emulsions via Nucleophile-Induced Covalent Surfactant Modifications” Chem. Mater., <\/em>2020,<\/strong> 32, <\/em> 4663\u20134671 <\/a>. (DOI: 10.1021\/acs.chemmater.0c01107)
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237)<\/a>

Gao, J.; Wu, P.; Fernandez, A.; Zhuang, J.; Thayumanavan, S. “Cellular AND Gates: Synergistic Recognition to Boost Selective Uptake of Polymeric Nanoassemblies\u201d Angew.Chem.Int.Ed., <\/em>2020,<\/strong> 59, <\/em>1-6<\/a>. (DOI: 10.1002\/anie.202002748) <\/p>\n<\/div><\/div>

235)<\/a>

Tsuei, M.; Shivrayan, M.; Kim, Y.; Thayumanavan, S.; Abbott, N.L. “Optical “Blinking” Triggered by Collisions of Single Supramolecular Assemblies of Amphiphilic Molecules with Interfaces of Liquid Crystals\u201d J. Am. Chem. Soc., <\/em>2020,<\/strong> 142, <\/em>6139\u20136148\u00a0<\/a>. (DOI: 10.1021\/jacs.9b13360) <\/p>\n<\/div><\/div>

234)<\/a>

Kumar, V.; Harris, J.T.; Ribbe, A.; Franc, M.; Bae, Y.; McNeil, A.J.; Thayumanavan, S. “Construction from Destruction: Hydrogel Formation from Triggered Depolymerization-Based Release of an Enzymatic Catalyst\u201d ACS Macro Lett., <\/em>2020,<\/strong> 9, <\/em> 377-381<\/a>. (DOI: 10.1021\/acsmacrolett.0c00023) <\/p>\n<\/div><\/div>

233)<\/a>

Zhuang, J.; Zhao, B.; Meng, X.; Schiffman, J.; Perry, S.L.; Vachet, R.W.; Thayumanavan, S. “A programmable chemical switch based on triggerable Michael acceptors\u201d Chem. Sci., <\/em>2020<\/strong>, 11, <\/em> 2103-2111<\/a>. (DOI: 10.1039\/C9SC05841A)
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228)<\/a>

Zentner, C.A.; Anson, F.; Thayumanavan, S.; Swager, T.M. “Dynamic Imine Chemistry at Complex Double Emulsion Interfaces\u201d J.Am.Chem.Soc <\/em>, 2019<\/strong>, 141, <\/em> 18048-18055 <\/a>. (DOI: 10.1021\/jacs.9b06852)
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221)<\/a>

Raghupathi, K.; Kumar, V.; Sridhar, U.; Ribbe, A.E.; He, H.; Thayumanavan, S. “Role of Oligoethylene Glycol Side Chain Length in Responsive Polymeric Nanoassemblies\u201d Langmuir, <\/em>2019<\/strong>, 35,<\/em> 7929-7936 <\/a>. (DOI: 10.1021\/acs.langmuir.9b00676)
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218)<\/a>

Jiang, Z.; Cui, W.; Mager, J.; Thayumanavan, S. “Postfunctionalization of Noncationic RNA-polymer Complexes for RNA Delivery\u201d Ind. Eng. Chem. Res. <\/em>2019<\/strong>, 58,<\/em> 6982-6991<\/a>. (DOI: 10.1021\/acs.iecr.9b00666)
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216)<\/a>

Zhuang, J.; Zhao, B.; Thayumanavan, S. “Cascaded Step-Growth Polymerization for Functional Polyamides with Diverse Architectures and Stimuli Responsive Characteristics\u201d ACS Macro Lett. <\/em>2019<\/strong>, 8,<\/em> 245\u2013249<\/a>. (DOI: 10.1021\/acsmacrolett.9b00094)
\n<\/p>\n<\/div><\/div>

213)<\/a>

Munkhbat, O.; Canakci, M.; Zheng, S.; Hu, W.; Osborne, B.; Bogdanov, A. A.; Thayumanavan, S. “19<\/sup>F MRI Imaging of Polymer Nanogels Aided by Improved Segmental Mobility of Embedded Fluorine Moieties\u201d Biomacromolecules <\/em>2019<\/strong>, 20,<\/em> 790\u2013800<\/a>. (DOI: 10.1021\/acs.biomac.8b01383)
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212)<\/a>

Jiang, Z.; Cui, W.; Prasad, P.; Touve, M. A.; Gianneschi, N. C.; Mager, J.; Thayumanavan, S. “Bait-and-Switch Supramolecular Strategy To Generate Noncationic RNA\u2013Polymer Complexes for RNA Delivery\u201d Biomacromolecules <\/em>2019<\/strong>, 20,<\/em> 435\u2013442<\/a>. (DOI: 10.1021\/acs.biomac.8b01321)
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211)<\/a>

Song, C.; Lin, T.; Zhang, Q.; Thayumanavan, S.; Ren, L. “pH-Sensitive Morphological Transitions in Polymeric Tadpole Assemblies for Programmed Tumor Therapy\u201d J. Control. Release <\/em>2019<\/strong>, 293,<\/em> 1-9<\/a>. (DOI: 10.1016\/j.jconrel.2018.10.033)
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210)<\/a>

He, H.; Liu, B.; Wang, M.; Vachet, R. W.; Thayumanavan, S. “Sequential Nucleophilic ‘Click’ Reactions for Functional Amphiphilic Homopolymers\u201d Polym. Chem. <\/em>2019<\/strong>, 10,<\/em> 187-193<\/a>. (DOI: 10.1039\/C8PY01341A)
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209)<\/a>

Zhuang, J.; Secinti, H.; Zhao, B.; Thayumanavan, S. “Propagation of Enzyme Induced Surface Events Inside Polymer Nanoassemblies for a Fast and Tunable Response\u201d Angew. Chem. Int. Ed. <\/em>2018<\/strong>, 57,<\/em> 7111-7115<\/a>. (DOI: 10.1002\/anie.201803029)
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208)<\/a>

Molla, M. R.; Rangadurai, P.; Antony, L.; Swaminathan, S.; de Pablo, J. J.; Thayumanavan, S. “Dynamic Actuation of Glassy Polymersomes through Isomerization of a Single Azobenzene Unit at the Block Copolymer Interface\u201d Nat. Chem. <\/em>2018<\/strong>, 10,<\/em> 659\u2013666<\/a>. (DOI: 10.1038\/s41557-018-0027-6)
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207)<\/a>

Serrano, M. A. C.; Gao, J.; Kelly, K. A.; Thayumanavan, S.; Vachet, R. W. “Supramolecular Polymeric Assemblies for the Selective Depletion of Abundant Acidic Proteins in Serum\u201d ACS Appl. Mater. Interfaces <\/em>2018<\/strong>, 10,<\/em> 40443\u201340451<\/a>. (DOI: 10.1021\/acsami.8b15976)
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205)<\/a>

Kim, Y.-K.; Raghupathi, K. R.; Pendery, J. S.; Khomein, P.; Sridhar, U.; de Pablo, J. J.; Thayumanavan, S.; Abbott, N. L. “Oligomers as Triggers for Responsive Liquid Crystals\u201d Langmuir <\/em>2018<\/strong>, 34,<\/em> 10092\u201310101<\/a>. (DOI: 10.1021\/acs.langmuir.8b01944)
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204)<\/a>

Leriche, G.; Manafirad, A.; Nguyen, S.; Bell, N.; Patterson, J. P.; Thayumanavan, S.; Yang, J.; Dinsmore, A. D.; Gianneschi, N. C. “Water Permeability and Elastic Properties of an Archaea Inspired Lipid Synthesized by Click Chemistry\u201d Chem. Mater. <\/em>2018<\/strong>, 30,<\/em> 3618\u20133622<\/a>. (DOI: 10.1021\/acs.chemmater.8b00992)
\n<\/p>\n<\/div><\/div>

199)<\/a>

Gordon, M. R.; Zhuang, J.; Ventura, J.; Li, L.; Raghupathi, K.; Thayumanavan, S. “Biodistribution Analysis of NIR-Labeled Nanogels using In Vivo FMT Imaging in Triple Negative Human Mammary Carcinoma Models\u201d Mol. Pharmaceutics <\/em>2018<\/strong>, 15,<\/em> 1180\u20131191<\/a>. (DOI: 10.1021\/acs.molpharmaceut.7b01011)
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198)<\/a>

Gordon, M. R.; Zhao, B.; Anson, F.; Fernandez, A.; Singh, K.; Homyak, C.; Canakci, M.; Vachet, R. W.; Thayumanavan, S. “Matrix Metalloproteinase-9 Responsive Nanogels for Proximal Surface Conversion and Activated Cellular Uptake\u201d Biomacromolecules <\/em>2018<\/strong>, 19,<\/em> 860-871<\/a>. (DOI: 10.1021\/acs.biomac.7b01659)
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197)<\/a>

Gao, J.; Liu, X.; Secinti, H.; Jiang, Z.; Munkhbat, O.; Xu, Y.; Guo, X.; Thayumanavan, S. “Photoactivation of Ligands for Extrinsically and Intrinsically Triggered Disassembly of Amphiphilic Nanoassemblies\u201d Chem. Eur. J. <\/em>2018<\/strong>, 24,<\/em> 1789\u20131794<\/a>. (DOI: 10.1002\/chem.201705217)
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194)<\/a>

Khomein, P.; Swaminathan, S.; Young, E. R.; Thayumanavan, S. “Fluorescence Enhancement Through Incorporation of Chromophores in Polymeric Nanoparticles\u201d J. Inorg. Organomet. Polym. Mater. <\/em>2018<\/strong>, 28,<\/em> 407-413<\/a>. (DOI: 10.1007\/s10904-017-0670-1)
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191)<\/a>

Raghupathi, K.; Eron, S. J.; Anson, F.; Hardy, J. A.; Thayumanavan, S. “Utilizing Inverse Emulsion Polymerization to Generate Responsive Nanogels for Cytosolic Protein Delivery\u201d Mol. Pharm. <\/em>2017<\/strong>, 14,<\/em> 4515\u20134524<\/a>. (DOI: 10.1021\/acs.molpharmaceut.7b00643)
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189)<\/a>

Dutta, K.; Hu, D.; Zhao, B.; Ribbe, A.; Zhuang, J.; Thayumanavan, S. “Templated Self-Assembly of a Covalent Polymer Network for Intracellular Protein Delivery and Traceless Release\u201d J. Am. Chem. Soc. <\/em>2017<\/strong>, 139,<\/em> 5676\u20135679<\/a>. (DOI: 10.1021\/jacs.7b01214)
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187)<\/a>

Raghupathi, K.; Thayumanavan, S. \u201cNano-Armoring of Enzymes: Rational Design of Polymer-Wrapped Enzymes\u201d Methods Enzymol. <\/em>2017<\/strong>, 590,<\/em> 381\u2013411<\/a>. (DOI: 10.1016\/bs.mie.2017.01.007) <\/p>\n<\/div><\/div>

186)<\/a>

Zhuang, J.; Garzoni, M.; Torres, D. A.; Poe, A.; Pavan, P. M.; Thayumanavan, S. \u201cProgrammable Nanoassemblies from Non-Assembling Homopolymers Using Ad\u2005Hoc Electrostatic Interactions\u201d Angew. Chem. Int. Ed. <\/em>2017<\/strong>, 56,<\/em> 4145\u20134149<\/a>. (DOI: 10.1002\/anie.201611688) <\/p>\n<\/div><\/div>

185)<\/a>

Liu, B.; Thayumanavan, S. \u201cSubstituent Effects on the pH Sensitivity of Acetals and Ketals and Their Correlation with Encapsulation Stability in Polymeric Nanogels\u201d J. Am. Soc. Chem. <\/em>2017<\/strong>, 139,<\/em> 2306\u20132317<\/a>. (DOI: 10.1021\/jacs.6b11181)
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181)<\/a>

Liu, X.; Ding, H.; Jiang, Z.; Zhuang, J.; Xu, Y.; Guo, X.; Thayumanavan, S. \u201cMulti-Stimuli-Responsive Amphiphilic Assemblies through Simple Postpolymerization Modifications\u201d Macromolecules <\/em>2016<\/strong>, 49,<\/em> 6186\u20136192<\/a>. (DOI: 10.1021\/acs.macromol.6b01397) <\/p>\n<\/div><\/div>

179)<\/a>

Rangadurai, P.; Molla, M. R.; Prasad, P.; Caissy, M.; Thayumanavan, S. \u201cTemporal and Triggered Evolution of Host-Guest Characteristics in Amphiphilic Polymer Assemblies\u201d J. Am. Chem. Soc. <\/em>2016<\/strong>, 138,<\/em> 7508\u20137511<\/a>. (DOI: 10.1021\/jacs.6b04099)
\n[Video<\/a>]
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177)<\/a>

Wang, H.; Zhuang, J.; Raghupathi, K. R.; Thayumanavan, S. \u201cA Supramolecular Dissociation Strategy for Protein Sensing\u201d Chem. Commun. <\/em>2015<\/strong>, 51,<\/em> 17265\u201317268<\/a>. (DOI: 10.1039\/C5CC07408H) <\/p>\n<\/div><\/div>

176)<\/a>

Prasad, P.; Molla, M. R.; Cui, W.; Canakci, M.; Osborne, B.; Mager, J.; Thayumanavan, S. \u201cPolyamide Nanogels from GRAS Components and Their Toxicity in Mouse Pre-implantation Embryos\u201d Biomacromolecules <\/em>2015<\/strong>, 16,<\/em> 3491\u20133498<\/a>. (DOI: 10.1021\/acs.biomac.5b00900) <\/p>\n<\/div><\/div>

174)<\/a>

Ventura, J.; Eron, S. J.; Gonz\u00e1lez-Toro, D. C.; Raghpathi, K. R.; Wang, F.; Hardy, J. A.; Thayumanavan, S. \u201cReactive Self-Assembly of Polymers and Proteins to Reversibly Silence a Killer Protein\u201d Biomacromolecules <\/em>2015<\/strong>, 16,<\/em> 3161\u20133171<\/a>. (DOI: 10.1021\/acs.biomac.5b00779) <\/p>\n<\/div><\/div>

170)<\/a>

Molla, M. R.; Prasad, P.; Thayumanavan, S. \u201cProtein\u2010Induced Supramolecular Disassembly of Amphiphilic Polypeptide Nanoassemblies\u201d J. Am. Chem. Soc. <\/em>2015<\/strong>, 137,<\/em> 7286-7289<\/a>. (DOI: 10.1021\/jacs.5b04285) (R,S)\"170\"<\/p>\n<\/div><\/div>

169)<\/a>

Song, C.; Li, L.; Dai, L.; Thayumanavan, S. \u201cResponsive Single Chain Polymer Nanoparticles with Host-Guest Features\u201d Polym. Chem. <\/em>2015<\/strong>, 6<\/em>, 4828-4834<\/a>. (DOI: 10.1039\/C5PY00600G) (R)<\/p>\n

\"169\"<\/p>\n<\/div><\/div>

168)<\/a>

Raghupathi, K. R.; Sridhar, U.; Byrne, K.; Raghupathi, K. R.; Thayumanavan, S. “Influence of Backbone Conformational Rigidity in Temperature-Sensitive Amphiphilic Supramolecular Assemblies” J. Am. Chem. Soc. <\/em>2015<\/strong>, 137, <\/em>5308-5311<\/a> (DOI: 10.1021\/jacs.5b02108). (R, S)\"168\"<\/a><\/p>\n<\/div><\/div>

167)<\/a>

Wang, Hui; Raghupathi, K.; Zhuang, J.; Thayumanavan, S. “Activatable Dendritic 19F Probes for Enzyme Detection” ACS Macro Letters, <\/em>2015<\/strong>, 4, <\/em>422-425 <\/a>(DOI: 10.1021\/acsmacrolett.5b00199). (R, S)\"167\"<\/a><\/p>\n<\/div><\/div>

165)<\/a>

Yuan, C.; Chang, Y.; Mao, J.; Yu, S.; Luo, W.; Xu, Y.; Thayumanavan, S.; Dai, L. \u201cSupramolecular Assembly of Crosslinkable Monomers for Degradable and Fluorescent Polymer Nanoparticles\u201d J. Mater. Chem. B.<\/em> , 2015<\/strong>, 2858-2866<\/a>\u00a0\u00a0(DOI: 10.1039\/c4tb01880j).\u00a0\u00a0(R,S)<\/p>\n

\"165\"<\/a><\/p>\n

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164)<\/a>

Li, L.; Song, C.; Jennings, M.; Thayumanavan, S. \u201cPhotoinduced Heterodisulfide Metathesis for Reagent-free Synthesis of Polymer Nanoparticles\u201d Chem. Commun. 2015<\/strong>, 51,<\/em> 1425-1428 <\/a>(DOI: 10.1039\/c4cc08000a). (R)<\/p>\n

\"164\"<\/a><\/p>\n<\/div><\/div>

163)<\/a>

Molla, M. R.; Rangadurai, P.; Pavan, G. M.; Thayumanavan, S. \u201cExperimental and Theoretical Investigations in Stimuli Responsive Dendrimer-based Assemblies\u201d Nanoscale, 2015<\/strong>, 7, <\/em>3817-3837 <\/a>(DOI: 10.1039\/C4NR04563G). (R,S)<\/p>\n

\"163\"<\/a><\/p>\n<\/div><\/div>

162)<\/a>

Molla, M. R.; Marcinko, T.; Prasad, P.; Deming, D.; Garman, S.; Thayumanavan, S. \u201cUnlocking a Caged Lysosomal Protein from a Polymeric Nanogel with a pH Trigger\u201d Biomacromolecules, 2014<\/strong>, 15<\/em>, 4046-4053<\/a> (DOI: 10.1021\/bm501091p). (R,S)<\/p>\n

\"162\"<\/a><\/p>\n<\/div><\/div>

161)<\/a>

Li, L.; Thayumanavan, S. \u201cEnvironment-Dependent Guest-Exchange in Supramolecular Hosts\u201d\u00a0Langmuir<\/em>, 2014<\/strong>, 30<\/em>, 12384-12390<\/a>\u00a0(DOI: 10.1021\/la502760c). (R,S)<\/p>\n

\"161\"<\/a><\/p>\n<\/div><\/div>

160)<\/a>

Li, L.; Yuan, C.; Dai, L.; Thayumanavan, S. “Thermo-responsive Polymeric Nanoparticles: Nucleation from Cooperative Polymerization Driven by Dative Bonds”\u00a0Macromolecules, 2014<\/strong>, 47<\/em>, 5869-5876<\/a>\u00a0(DOI: 10.1021\/ma5015808). (R,S)<\/p>\n

\"160\"<\/a><\/p>\n<\/div><\/div>

156)<\/a>

Raghupathi, K.; Guo, J.; Munkhbat, O.; Rangadurai, P.; Thayumanavan, S. \u201cSupramolecular Assembly and Disassembly of Facially Amphiphilic Dendrimers\u201d\u00a0Acc. Chem. Res. 2014<\/strong>,\u00a047<\/em>, 2200-2211 (Invited Review)<\/a>\u00a0\u00a0(DOI: 10.1021\/ar500143u)\u00a0(PMCID# PMC4100797).\u00a0(R,S)<\/p>\n

\"156\"<\/a><\/p>\n<\/div><\/div>

155)<\/a>

Amado Torres, D.; Garzoni, M.; Subrahmanyam, A.; Pavan, G. M.; Thayumanavan, S. <\/i>“Protein-Triggered Supramolecular Disassembly: Insights Based on Variations in Ligand Location in Amphiphilic Dendrons” J. Am. Chem. Soc. <\/i>2014<\/b>, 136<\/i>, 5385-5399.<\/a> (DOI:<\/strong> 10.1021\/ja500634u ) (R,S) \"155\"<\/a><\/p>\n<\/div><\/div>

153)<\/a>

Guo, J.; Zhuang, J.; Wang, F.; Raghupathi, K.; Thayumanavan, S. “Protein AND Enzyme Gated Supramolecular Disassembly” \u00a0J. Am. Chem. Soc.<\/em> 2014<\/strong>, 136<\/em>, 2220-2223<\/a>\u00a0\u00a0\u00a0(DOI: 10.1021\/ja4108676) (R,S).\u00a0<\/span><\/p>\n

\"153\"<\/a><\/p>\n<\/div><\/div>

150)<\/a>

Zhuang, J.; Chacko, R.; Amado Torres, D.; Wang, H.; Thayumanavan, S. “Dual Stimuli \u2013 Dual Response Nanoassemblies Prepared from a Simple Homopolymer” ACS Macro Lett. <\/i>2014<\/b>, 3<\/i>, 1-5<\/a> (DOI: 10.1021\/mz400515s) (R,S).<\/p>\n

\"150\"<\/a><\/p>\n<\/div><\/div>

149)<\/a>

<\/p>\n

<\/p>\n

<\/p>\n

<\/p>\n

Raghupathi, K.; Li, L.; Ventura, J.; Jennings, M.; Thayumanavan, S. \u201cpH Responsive Soft Nanoclusters with Size and Charge Conversional Features\u201d Polym. Chem. <\/i>2014<\/b>, 5<\/i>, 1737-1742.<\/a> (DOI:10.1039\/C3PY01277H) (R,S)<\/p>\n

\"149\"<\/a><\/p>\n<\/div><\/div>

148)<\/a>

Yuan, C.; Raghupathi, K.; Popere, B. C.; Ventura, J.; Dai, L.; Thayumanavan, S. \u201cComposite Supramolecular Nanoassemblies with Independent Stimulus Sensitivities”\u00a0 Chem. Sci.<\/i> 2014<\/b>, 5<\/i>, 229-234.<\/a> (DOI:10.1039\/C3SC52347K) (R,S)<\/p>\n

 <\/p>\n

\"148\"<\/a><\/p>\n<\/div><\/div>

147)<\/a>

<\/p>\n

<\/p>\n

Wang, H.; Zhuang, J.; Thayumanavan, S. \u201c“Functionalizable Amine-based Polymer Nanoparticles” <\/span>ACS Macro Lett. <\/span>2013<\/span><\/b>, 2<\/i>, 948-951.<\/span><\/a> (DOI: <\/strong>10.1021\/mz4004248) (R,S)<\/span><\/p>\n

\"147\"<\/a><\/p>\n<\/div><\/div>

144)<\/a>

<\/p>\n

<\/p>\n

Li, L.; Raghupathi, K.; Yuan, C.; Thayumanavan, S. \u201cSurface Charge Generation in Nanogels for Activated Cellular Uptake at Tumor-Relevant pH\u201d <\/span>Chem. Sci. 2013<\/b>, 4<\/em>, 3654-3660.<\/a> (DOI: 10.1039\/C3SC50899D) <\/span>(R,S)\"144\"<\/a><\/p>\n

 <\/p>\n<\/div><\/div>

143)<\/a>

Fuller, J.; Raghupathi, K.; Ramireddy, R. R.; Subrahmanyam, A.; Yesilyurt, V.; Thayumanavan, S. \u201cTemperature-Sensitive Transitions Below LCST in Amphiphilic Dendritic Assemblies \u2013 Host-Guest Implications\u201d\u00a0J. Am. Chem. Soc.<\/em> 2013<\/strong>, 135, <\/em>8947-8954.<\/a> (DOI: 10.1021\/ja402019c) (R,S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

142)<\/a>

Zhuang, J.; Gordon, M.; Ventura, J.; Li, L. Thayumanavan, S. \u201cMulti-Stimuli Responsive Macromolecules and Their Assemblies\u201d Chem. Soc. Rev.<\/i> 2013<\/b>, 42<\/em>, 7421-7435.<\/a><\/span> (DOI: 10.1039\/C3CS60094G) (R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

141)<\/a>

Gonz\u00e1lez-Toro, D.; Thayumanavan, S. “Advances in Polymer and Polymeric Nanostructures for Protein Conjugation” Eur. Poly. J. <\/a><\/em>2013<\/strong><\/a>, 49, <\/a><\/em>2906-2918<\/a>.<\/a> <\/em> (DOI: 10.1016\/j.eurpolymj.2013.05.002) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

140)<\/a>

Matsumoto, N.; Gonzalez-Toro, D.; Chacko, R.; Maynard, H. D.; Thayumanavan, S. \u201cSynthesis of Nanogel-Protein Conjugates\u201d Polymer Chem.<\/em> 2013<\/strong>, 4, 2464-2469.<\/a> (DOI: 10.1039\/c3py00085k) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

139)<\/a>

Li, L.; Ryu, J.; Thayumanavan, S. “Effect of Hofmeister Ions on the Size and Encapsulation Stability in Polymer Nanogels” Langmuir<\/em>, 2013<\/strong>, 29<\/em>, 50-55.<\/a> (DOI: 10.1021\/la3033463) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

138)<\/a>

Bickerton, S.; Jiwpanich, S.; Thayumanavan, S. \u201cInterconnected Roles of Scaffold Hydrophobicity, Drug Loading and Encapsulation Stability in Polymeric Nanocarriers\u201d Mol. Pharm.<\/em> 2012<\/strong>, 9<\/em>, 3569-3578.<\/a> (DOI: 1021\/mp3004226) (R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

134)<\/a>

Gonzalez-Toro, D.; Ryu, J.-H.; Chacko, R.; Zhuang, J.; Thayumanavan, S. “Concurrent Binding and Delivery of Proteins and Lipophilic Small Molecules Using Polymeric Nanogels” J. Am. Chem. Soc. 2012<\/strong>, 134, 6964-6967.<\/a><\/em> (DOI: 10.1021\/ja3019143) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

133)<\/a>

Ryu, J.; Bickerton, S.; Zhuang, J.; Thayumanavan, S. “Ligand-Decorated Nanogels: Fast One-Pot Synthesis and Cellular Targeting” Biomacromolecules,<\/em> 2012,<\/strong> 13,<\/em> 1515-1522.<\/a> (DOI: 10.1021\/bm300201x) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

130)<\/a>

Chacko, R.; Ventura, J.; Zhuang, J.; Thayumanavan, S. \u201cPolymer Nanogels: A Versatile Nanoscopic Drug Delivery Platform\u201d Adv. Drug Deliv. Rev.<\/em> 2012<\/strong>, 64<\/em>, 836-851. (Invited Perspective)<\/a> (DOI: 10.1016\/j.addr.2012.02.002) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

127)<\/a>

Zhuang, J.; Jiwpanich, S.; Deepak, V. D.; Thayumanavan, S. “Facile Preparation of Nanogels Using Activated Ester Containing Polymers” ACS Macro Lett.<\/em> 2012<\/strong>, 1<\/em>, 175-179.<\/a> (DOI: 10.1021\/mz200123f) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

115)<\/a>

Ryu, J.-H.; Chacko, R.; Jiwpanich, S.; Bickerton, S.; Babu, R. P.; Thayumanavan, S. \u201cSelf-Crosslinked Polymer Nanogels: a Versatile Nanoscopic Drug Delivery Platform” J. Am. Chem. Soc.<\/em> 2010<\/strong>, 132<\/em>, 17227-17235.<\/a> (DOI: 10.1021\/ja1069932) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

114)<\/a>

Jiwpanich, S.; Ryu, J.-H.; Bickerton, S.; Thayumanavan, S. \u201cNoncovalent Encapsulation Stability in Supramolecular Nanoassemblies” J. Am. Chem. Soc.<\/em> 2010<\/strong>, 132<\/em>, 10683-10685.<\/a> (DOI: <\/strong>10.1021\/ja105059g) (R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

111)<\/a>

Satav, S.; Bhat, S.; Thayumanavan, S. \u201cFeedback Regulated Drug Delivery Vehicles: Carbon Dioxide Responsive Cationic Hydrogels for Antidote Release\u201d Biomacromolecules<\/em>, 2010<\/strong>, 11<\/em>, 1735-1740.<\/a> (DOI: 10.1021\/bm1005454) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

110)<\/a>

Ryu, J.-H.; Jiwpanich, S.; Chacko, R.; Bickerton, S.; Thayumanavan, S. \u201cSurface-Functionalizable Polymer Nanogels with Facile Hydrophobic Guest Encapsulation Capabilities” J. Am. Chem. Soc.<\/em> 2010<\/strong>, 132<\/em>, 8246-8247.<\/a> (DOI: <\/strong>10.1021\/ja102316a) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

99)<\/a>

Ryu, J.; Park, S.; Kim, B.; Klaikherd, A.; Russell, T. P.; Thayumanavan, S. \u201cHighly Ordered Gold Nanotubes using Thiols at a Cleavable Block Copolymer Interface\u201d J. Am. Chem. Soc. 2009<\/strong>, 131, <\/a><\/em>9870-9871<\/a>.<\/a> <\/em>(<\/strong>DOI<\/abbr>: <\/span>10.1021\/ja902567p) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

97)<\/a>

Roy, R.; Jerry, D. J.; Thayumanavan, S. \u201cVirus-Inspired Approach to Nonviral Gene Delivery Vehicles\u201d Biomacromolecules<\/em>, 2009<\/strong>, 10<\/em>, 2189-2193.<\/a> (DOI<\/abbr>:<\/span> <\/strong>10.1021\/bm900370p) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

92)<\/a>

Klaikherd, A.; Chikkanagari, N.; Thayumanavan, S. \u201cMulti-Stimuli Sensitive Amphiphilic Block Copolymer Assemblies\u201d J. Am. Chem. Soc.<\/em> 2009<\/strong>, 131<\/em>, 4830-4838.<\/a> (DOI<\/abbr>:<\/span> <\/strong>10.1021\/ja809475a) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

89)<\/a>

Ghosh, S.; Yesilyurt, V.; Savariar, E. N.; Irvin, K.; Thayumanavan, S. \u201cRedox, Ionic Strength, and pH Sensitive Supramolecular Polymer Assemblies\u201d J. Poly. Sci. Part A: Poly. Chem.<\/em> 2009<\/strong>, 47<\/em>, 1052-1060.<\/a> (DOI:\u00a010.1002\/pola.23204) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

87)<\/a>

Savariar, E. N.; Sochat, M. M.; Klaikherd, A.; Thayumanavan, S. \u201cFunctional Group Density and Recognition in Polymer Nanotubes\u201d Angew. Chem. Int. Ed.<\/em> 2009<\/strong>, 48<\/em>, 110-114.<\/a> (DOI:\u00a010.1002\/anie.200804136) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

85)<\/a>

Savariar, E. N.; Ghosh, S.; Gonz\u00e1lez, D. C.; Thayumanavan, S. \u201cDisassembly of Noncovalent Amphiphilic Polymers with Proteins and Utility in Pattern Sensing\u201d J. Am. Chem. Soc.<\/em> 2008<\/strong>, 130<\/em>, 5416-5417<\/a>.\u00a0 (DOI: <\/strong>10.1021\/ja800164z) (R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

83)<\/a>

Klaikherd, A.; Ghosh, S.; Thayumanavan, S. \u201cA Facile Method for the Synthesis of Cleavable Block Copolymers from ATRP-based Homopolymers\u201d Macromolecules,<\/em> 2007<\/strong>, 40<\/em>, 8518-8520.<\/a> (DOI: <\/strong>10.1021\/ma071852n) (R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

80)<\/a>

Ghosh, S.; Irvin, K.; Thayumanavan, S. \u201cTunable Disassembly of Micelles Using a Redox Trigger\u201d Langmuir<\/em> 2007<\/strong>, 23<\/em>, 7916-7919.<\/a> (DOI: <\/strong>10.1021\/la700981z) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

79)<\/a>

Kim, Y.J.; Shin, D.; Vutukuri, D.; Savariar, E.N.; Kim, S.Y.; Thayumanavan, S.; Russell, T.P. \u201cGlobular Organization of Multifunctional Linear Homopolymer Using Trifunctional Molecules\u201d Macromolecules<\/em>, 2007<\/strong>, 40<\/em>, 4267-4275.<\/a> (DOI: <\/strong>10.1021\/ma070170x) (R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

75)<\/a>

Ambade, A. V.; Savariar, E. N.; Thayumanavan, S. \u201cDendritic Nanostructures for Cancer Therapy\u201d Nanotechnology for Cancer Therapy<\/em>, 2007<\/strong>, 509-521. (invited review).<\/a> (DOI: 10.1201\/9781420006636.ch26) (R, S)<\/p>\n<\/div><\/div>

67)<\/a>

Ghosh, S.; Basu, S.; Thayumanavan, S. \u201cSimultaneous and Reversible Functionalization of Copolymers for Biological Applications\u201d Macromolecules<\/em>, 2006<\/strong>, 39<\/em>, 5595-5597.<\/a> (DOI: 10.1021\/ma061420x) <\/strong>(R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

66)<\/a>

Roy, R.; Sandanaraj, B. S.; Klaikherd, A.; Thayumanavan, S. \u201cTuning Substrate Selectivity of a Cationic Enzyme Using Cationic Polymers\u201d Langmuir,<\/em> 2006<\/strong>, 22<\/em>, 7695-7700.<\/a> (DOI: <\/strong>10.1021\/la060496j) (R, S)
\n\"\"<\/a><\/p>\n<\/div><\/div>

53)<\/a>

Jiang, J.; Thayumanavan, S. \u201cSynthesis and Characterization of Amine-Functionalized Polystyrene Nanoparticles\u201d Macromolecules, 2005<\/strong>, 38, <\/a><\/em>5886-5891.<\/a> (DOI: 10.1021\/ma0507286) (S, R)
\n\"\"<\/a><\/p>\n<\/div><\/div>

47)<\/a>

Savariar, E. N.; Thayumanavan, S. \u201cControlled Polymerization of N<\/em>-isopropylacrylamide with an Activated Methacrylic Ester\u201d J. Poly. Sci. Part A: Poly. Chem.<\/em> 2004<\/strong>, 42<\/em>, 6340-6345.<\/a> (DOI:10.1002\/pola.20467) (S, R)<\/p>\n

\"\"<\/a><\/p>\n<\/div><\/div>

46)<\/a>

Basu, S.; Vutukuri, D.; Shyamroy, S.; Sandanaraj, B.S.; Thayumanavan, S. \u201cInvertible Amphiphilic Polymers\u201d J. Am. Chem. Soc.<\/em> 2004<\/strong>, 126<\/em>, 9890-9891.<\/a> (DOI: <\/strong>10.1021\/ja047816a) (S, R)<\/p>\n

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