Dr. Hui Xiao

Dr. Hui Xiao, PhD’2004  (Currently Staff Scientist at Regeneron Pharmaceuticals, Inc.)

Dissertation title: Probing protein small ligand binding dynamics by hydrogen/deuterium exchange and electrospray ionization mass spectrometry

Representative publications:

  • H. Xiao and I.A. Kaltashov, et al. Mapping protein energy landscapes with amide hydrogen exchange and mass spectrometry: I. A generalized model for a two-state protein and comparison with experiment. Protein Sci. 200514, 543-557.
  • H. Xiao and I.A. Kaltahov, Transient structural disorder as a facilitator of protein-ligand binding: native H/D exchange-mass spectrometry study of cellular retinoic acid binding protein I. J. Am. Soc. Mass Spectrom. 2005, 16, 869-789.

click here to see all papers co-authored by Dr. Hui Xiao based on his work at UMass-Amherst