Welcome to the
Chen Research Group!

~Protein Nanopores~

Research in the Chen group focuses on membrane proteins, specifically pore-forming proteins (PFP). We aim to understand the folding, assembly, dynamics and functional mechanism of PFPs. In parallel, we use what we learn about PFPs to develop biotechnological applications for sensing disease markers and treating cancer. To achieve our goal, the research in Chen’s lab uses a combination of approaches in molecular biology, biochemistry and biophysics.