(52)     Chaplin VD, Hangasky JA, Huang HT, Duan R, Maroney MJ, Knapp MJ. “Chloride Supports O2 Activation in the D201G Facial Triad Variant of Factor-Inhibiting Hypoxia Inducible Factor, an α-Ketoglutarate Dependent Oxygenase.” Inorg. Chem. (2018) 57:12588–12595 doi: 10.1021/acs.inorgchem.8b01736.

(51)     Iyer SR, Chaplin VD, Knapp MJ, Solomon EI.” O2 Activation by Nonheme FeII α-Ketoglutarate-Dependent Enzyme Variants: Elucidating the Role of the Facial Triad Carboxylate in FIH.” J. Amer. Chem. Soc. (2018) 140:11777-11783. doi: 10.1021/jacs.8b07277

(50)     Chaplin VD, Valliere MA, Hangasky JA, Knapp MJ “Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).” J Inorg Biochem. (2018) 178:63-69. 10.1016/j.jinorgbio.2017.10.001.

(49)     VD Chaplin, AN Barbato, MJ Knapp,* 2017.  “Mammalian O2 Sensing and Signaling,” Chapter 7 in Gas Sensing in Cells, RSC publishers, S. Aono, Ed. (2017) DOI 10.1039/9781788012836-00219.

(48)     JA Hangasky, CY Taabazuing, CB Martin, SJ Eron, SC Garman, MJ Knapp* “The facial triad in the alpha-ketoglutarate oxygenase FIH: a role for sterics in linking substrate binding to O2 activation” J. Inorg. Biochem, 166(2017):26-33.

(47)     Taabazuing, CY; Fermann, J; Garman, S; Knapp, MJ.* “Substrate promotes productive gas binding in the αKG-dependent oxygenase FIH” Biochemistry, (2016) 55(2):277-86.

(46)     Pektas S, Taabazuing CY, Knapp MJ.* “Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2.” Biochemistry (2015) 54(18):2851-7.

(45) Hangasky, J. A.; Gandhi, H.; Valliere, M. A.; Ostrom, N. E.; Knapp, M. J. “The Rate-Limiting Step of O2 activation in the a-Ketoglutarate Oxygenase Factor Inhibiting Hypoxia Inducible Factor,“ Biochemistry, 2014, 53, pp 8077–8084

(44) Hangasky, J. A.; Ivison, G. T.; Knapp, M. J. “Substrate Positioning by Gln239 Stimulates Turnover in Factor Inhbiting HIF, an aKG-dependent hydroxylase,“ Biochemistry, 2014, 53, pp 5750–5758

(43) Taabazuing, C. Y.; Hangasky, J. A.; Knapp, M. J. “Oxygen Sensing Strategies in Mammals and Bacteria,“ J. Inorg. Biochem. 2014, 133, pp 63–72

(42) Light, K. M.; Hangasky, J. A.; Knapp, M. J.; Solomon, E. I. “First- and second-sphere contributions to Fe(II) site activation by cosubstrate binding in non-heme Fe enzymes,“ Dalton Trans., 2014, 43, pp 1505–1508

(41) Pektas, S.; Knapp, M. J. “Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change,“ J. Inorg. Biochem., 2013, 126, pp 55–60

(40) Light, K. M.; Hangasky, J. A.; Knapp, M. J.; Solomon, E. I. “Spectroscopic Studies of the Mononuclear Nonheme Fell Enzyme FIH: Second-Sphere Contributions to Reactivity,“ J. Amer. Chem. Soc., 2013, 135 (26), pp 9665–9674

(39) Hangasky, J. A.; Taabazuing, C. Y.; Valliere, M. A.; Knapp, M. J. “Imposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the alpha KG dependent oxygenases ,“ Metallomics, 2013, 5 (4), pp 287–301

(38) Hangasky, J. A.; Saban, E.; Knapp, M. J. “Inverse Solvent Isotope Effects Arising from Substrate Triggering in the Factor Inhibiting Hypoxia Inducible Factor,“ Biochemistry, 2013, 52 (9), pp 1594–1602

(37) Flagg, S. C.; Giri, N.; Pektas, S.; Maroney, M. J.; Knapp, M. J. “Inverse Solvent Isotope Effects Demonstrate Slow Aquo Release from Hypoxia Inducible Factor-Prolyl Hydroxylase (PHD2),“ Biochemistry, 2012, 51 (33), pp 6654–6666

(36) Flagg, S. C.; Martin, C. B.; Taabazuing, C. Y.; Knapp, M. J. “Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH),“ J. Inorg. Biochem., 2012, 113, pp 25–30

(35) Saban, E.; Chen, Y.-H.; Hangasky, J. A.; Taabazuing, C. Y.; Holmes, B. E.; Knapp, M. J. “The Second Coordination Sphere of FIH Controls Hydroxylation,“ Biochemistry, 2011, 50 (21), pp 4733–4740

(34) Saban, E.; Flagg, S. C.; Knapp, M. J. “Uncoupled O-2 activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species,“ J. Inorg. Biochem. 2011, 105 (5), pp 630–636

(33) Meaghan E. Germain, Michael J. Knapp. “Optical explosives detection: from color changes to fluorescence turn-on,“ Chem. Soc. Rev., 2009, 38 (9), pp 2543–2555

(32) Carver, A. C.; De, M.; Bayraktar, H.; Rana, S.; Rotello, V. M.; Knapp, M. J.* “Intermolecular Electron-Transfer Catalyzed on Nanoparticle Surfaces,“ J. Am. Chem. Soc., 2009, 131 (11), pp 3798–3799

(31) Carver, A. C.; Knapp, M. J.* “Electron and energy transfer reactions of [Ru(bpy)3]2+*/3+ with copper-phenolates,” Polyhedron 2008, 27, 3313

(30) Chen, Y.-H.; Comeaux, L. M.; Herbst, R. M.; Saban, E.; Kennedy, D. C.; Maroney, M. J.; Knapp, M. J.* “Coordination changes and auto-hydroxylation of FIH-1: uncoupled O2-activation in a human hypoxia sensor,” J. Inorg. Biochem. 2008, accepted for a special “Young Investigators Issue.” J. Inorg. Biochem.Volume 102, Issue 12, December 2008, 2120-2129

(29) Germain, M. E.; Knapp, M. J.* “Turn-on fluorescence detection of H2O2 and TATP,” Inorg. Chem., 2008, 47 (21), pp 9748–9750.

(28) Germain, M. E.; Vargo, T. R.; McClure, B. A.; Rack, J. J.; Van Patten, P. G.; Odoi, M.; Knapp, M. J.* “Quenching Mechanism of Zn(Salicylaldimine) by Nitroaromatics,” Inorg. Chem. 2008, 47, 6203-6211.

(27) Germain, M. E.; Knapp,* M. J. “Discrimination of nitroaromatics and explosives mimics by a fluorescent Zn(salicylaldimine) sensor array”, J. Am. Chem. Soc. 2008 130 (16), 5422

(26) Chen, Y.-H.; Comeaux, L. M.; Eyles, S. J.; Knapp, M. J. “Auto-hydroxylation of FIH-1, an Fe(II), α-ketoglutarate dependent human hypoxia sensor,” Chem. Commun. 2008

(25) Bayraktar, H, Srivastava, S.; You, C.-C.; Rotello,* V. M.; Knapp,* M. J. “Controlled nanoparticle assembly through protein conformational changes,” Soft Matter 2008 4, 751-756 (cover article)

(24) Bayraktar, H.; You, C.-C.; Rotello, V. M.; Knapp, M. J. “Facial Control of Nanoparticle Binding to Cytochrome c” J. Am. Chem. Soc., 2007, 129, 2732-2733.

(23) Meaghan E. Germain, Thomas R. Vargo, Peter G. Khalifah and Michael J. Knapp, “Fluorescent detection of nitroaromatics and 2,3-dimethyl 2,3-dinitrobutane (DMNB) by a zinc complex: (L)Zn” Inorg. Chem., 2007, 46, 4422-4429.

(22) Britto S. Sandanaraj, Halil Bayraktar, Kothandam Krishnamoorthy, Michael J. Knapp and Sankaran Thayumanavan, “Recognition and Modulation of Cytochrome c’s Redox Properties by an Amphiphilic Homopolymer” Langmuir, 2007, 23, 3891-3897.

(21) You, C.-C.; Agasti,S. S.; De, M.; Knapp, M. J.; Rotello, V. M.; “Modulation of the Catalytic Behavior of a-Chymotrypsin at Monolayer-Protected Nanoparticle Surfaces,” J. Am. Chem. Soc., 2006, 128, 14612-14618.

(20) Bayraktar, H.; Ghosh, P. S.; Rotello, V. M.; Knapp, M. J. “Disruption of protein-protein interactions using nanoparticles: inhibition of cytochrome c peroxidase,” Chem. Comm. 2006, 13, 1390-1392.

(19) Knapp, M. J.; Meyer, M. M.; Klinman, J. P. In Handbook of Hydrogen Transfer, Vol; 2: Biological Aspects of Hydrogen Transfer; Schowen, R. L., Klinman, J. P., Eds.; Wiley VCH: Weinheim, 2006.

(18) Knapp, M. J.; Klinman, J. P. “Kinetic studies of oxygen reactivity in soybean lipoxygenase-1,” Biochemistry 2003, 42, 11466-11475.

(17) Sanudo, E. C.; Grillo, V. A.; Knapp, M. J.; Bollinger, J. C.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Tetranuclear manganese complexes with dimer-of-dimer and ladder structures from the use of a bis-bipyridyl ligand,” Inorg. Chem. 2002, 41, 2441-2450.

(16) Francisco, W. A.; Knapp, M. J.; Blackburn, N. J.; Klinman, J. P. “Hydrogen tunneling in peptidylglycine alpha-hydroxylating monooxygenase,” J. Am. Chem. Soc. 2002, 124, 8194-8195.

(15) Knapp, M. J.; Klinman, J. P. “Environmentally coupled hydrogen tunneling – Linking catalysis to dynamics,” Eur. J. Biochem. 2002, 269, 3113-3121.

(14) Knapp, M. J.; Rickert, K.; Klinman, J. P. “Temperature-dependent isotope effects in soybean lipoxygenase-1: Correlating hydrogen tunneling with protein dynamics,” J. Am. Chem. Soc. 2002, 124, 3865-3874.

(13) Knapp, M. J.; Seebeck, F. P.; Klinman, J. P. “Steric control of oxygenation regiochemistry in soybean lipoxygenase-1,” J. Am. Chem. Soc. 2001, 123, 2931-2932.

(12) Krzystek, J.; Telser, J.; Knapp, M. J.; Hendrickson, D. N.; Aromi, G.; Christou, G.; Angerhofer, A.; Brunel, L. C. “High-frequency and -field electron paramagnetic resonance of high-spin manganese(III) in axially symmetric coordination complexes,” Appl. Magn. Reson. 2001, 21, 571-585.

(11) Maes, E. M.; Knapp, H. J.; Czernuszewicz, R. S.; Hendrickson, D. N. “Ligand conformational effects on the resonance Raman signature of [Fe4S4(SAryl)4]2- clusters,” J. Phys. Chem. B 2000, 104, 10878-10884.

(10) Knapp, M. J.; Krzystek, J.; Brunel, L. C.; Hendrickson, D. N. “High-frequency EPR study of the ferrous ion in the reduced rubredoxin model [Fe(SPh)4]2-,” Inorg. Chem. 2000, 39, 281-288.

(9) Brechin, E. K.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “New hexanuclear and octanuclear iron(III) oxide clusters: octahedral [Fe6O2]14+ species and core isomerism in [Fe8O4]16+ complexes,” Inorg. Chim. Acta 2000, 297, 389-399.

(8) Aromi, G.; Knapp, M. J.; Claude, J. P.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “High-spin molecules: Hexanuclear Mn-III clusters with [Mn6O4X4]6+ (X = Cl-, Br-) face-capped octahedral cores and S=12 ground states,” J. Am. Chem. Soc. 1999, 121, 5489-5499.

(7) Knapp, M. J.; Krzystek, J.; Brunel, L. C.; Hendrickson, D. N. “High-field EPR study of resonance-delocalized [Fe2(OH)3(tmtacn)2]2+,” Inorg. Chem. 1999, 38, 3321-3328.

(6) Grant, C. M.; Stamper, B. J.; Knapp, M. J.; Folting, K.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Syntheses, crystal structures and properties of mononuclear chromium(III) and dinuclear vanadium(III) and copper(II) complexes with a bis-bipyridyl ligand,” J. Chem. Soc. Dalton 1999, 3399-3405.

(5) Grant, C. M.; Knapp, M. J.; Streib, W. E.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Dinuclear and hexanuclear iron(III) oxide complexes with a bis(bipyridine) ligand: A new [Fe6(m3-O)4]10+ core,” Inorg. Chem. 1998, 37, 6065-6070.

(4) Seela, J. L.; Knapp, M. J.; Kolack, K. S.; Chang, H. R.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “Structural and magnetochemical properties of mono-, di-, and trinuclear Manganese(III) dithiolate complexes,” Inorg. Chem. 1998, 37, 516-525.

(3) Grant, C. M.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “A new structural type in iron carboxylate cluster chemistry via use of bis-bipyridine ligands: [Fe6O4Cl4(O2CPh)4L-2][FeCl4]2,” Chem. Comm. 1998, 1753-1754.

(2) Aromi, G.; Claude, J. P.; Knapp, M. J.; Huffman, J. C.; Hendrickson, D. N.; Christou, G. “High-spin molecules: Hexanuclear [Mn6O4Cl4(Me2dbm)6] (Me2dbmH = 4,4 ‘-dimethyldibenzoylmethane) with a near tetrahedral [Mn6O4Cl4]6+ core and a S=12 ground state,” J. Am. Chem. Soc. 1998, 120, 2977-2978.

(1) Grillo, V. A.; Knapp, M. J.; Bollinger, J. C.; Hendrickson, D. N.; Christou, G. “Bis(bipyridine) ligands in manganese carboxylate cluster chemistry: Self-assembly of a cluster complex with two butterfly-like [Mn4(m3-O)2]8+ cores,” Angew. Chem. Int. Ed. 1996, 35, 1818-1820.