News

2022

June 08, 2022   Mingxu has been promoted to Associate Professor with Tenure!

May 25, 2022   Mingxu is now an associate editor of the analytical chemistry section of Frontiers in Chemistry, new submissions are welcome!

May 16, 2022   Undergrad student from McGill University, Anastasiya Kaltashova, joins the lab for summer research.  Welcome, Anastasiya!

May 05, 2022   Our invited review describing recent progress of applying lipid-DNA conjugates for studying cell membrane biophysics has been accepted by Quarterly Rev Biophys.

April 5, 2022   Qian Tian will take a 3-month summer internship at Dyne Therapeutics.  Congrats!

March 18, 2022    Jikun Wang has received an Oliver Zajicek Memorial Scholarship Award.  Congrats, Jikun!

March 18, 2022   Kevin Alexander has received a J.F.B. Fund for undergraduate research during summer.  Congrats, Kevin!

March 08, 2022   Our invited review describing recent development of DNA-based mechanical sensors and regulators has been accepted by Chem Comm in a special issue of Emerging Investigators.

February 18, 2022   Ahsan Ausaf Ali will take a 10-week summer internship at Takeda Pharmaceuticals.  Congrats!

January 25, 2022   A microbiology major undergrad, Michelle Moskvitch, and a biochemistry major Kevin Alexander join the lab.  Welcome!

2021

December 20, 2021   Dr. Yuanchang Liu joins the lab as a research fellow.  Welcome!

December 09, 2021   Congrats Rigumula Wu on passing her thesis defense!  The Ph.D. #4 from our lab!  Good luck at Genentech.

December 08, 2021   Jennings Sun receives the Paul Hatheway Terry Scholarship in recognition of his research and academic standing.  Congrats, Jennings!

December 02, 2021   Congrats Puspam Keshri on passing his thesis defense!  The Ph.D. #3 from our lab!  Puspam will join Laronde (Endless RNA Therapeutics) afterwards.

November 12, 2021   Our paper describing a DNA hybridization-based approach for imaging membrane order and transient interactions in living cells has been accepted by Angew Chem Int Ed

September 06, 2021   We are on Twitter now!  Follow us @UMass_YouLab.

September 06, 2021   Our paper describing a RNA-based sensor that enables for the first time the live-cell imaging of (p)ppGpp has been accepted by Angew Chem Int Ed

September 01, 2021   Two biochemistry major undergrads, Sarthak Srivastava and Simon Kangoun, join the lab.  Welcome!

August 24, 2021   During ResearchFest 2021, Rigumula Wu is awarded a William E McEwen Scholarship Fund Award for oral presentation.  Ru Zheng is a First Place winner of Marvin D. Rausch Scholarship Award for outstanding poster presentation.  Congrats, Rigumula and Ru!, joins the lab.  Welcome!

August 05, 2021   Congrats Yousef Bagheri on passing his thesis defense!  The second Ph.D. from our lab!  Yousef will join the Sarah Veatch Lab at the University of Michigan as a postdoc fellow.

July 28, 2021   Congrats Qikun Yu on passing his thesis defense!  The first You Lab Ph.D.!  Qikun will join the PTC Therapeutics as an RNA biology scientist.

July 13, 2021   Our invited paper describing a recently developed software for engineering genetically encoded RNA nanodevices has been accepted by Trends in Chemistry.

July 12, 2021   Mingxu has received 2020-21 Burlew Award from Connecticut Valley Section of American Chemical SocietyThanks, CVS – ACS!

June 19, 2021   Our collaborative paper describing a photodiode-based on-chip ratiometric aptamer sensor for detecting cytokine dynamics has been accepted by Sensors Actuators B: Chem.

June 11, 2021   Ru Zheng has been awarded 2-year UMass Chemistry-Biology Interface Fellowship.  Congrats, Ru!

June 05, 2021   Our invited book chapter describing rational design of allosteric fluorogenic RNA sensors has now been published in RNA Scaffolds, part of Methods in Molecular Biology book seriesSpringer.

June 01, 2021   CURE-REU undergrad student from Holyoke Community College, Anastasia Antropova, joins the lab for summer research.  Welcome, Anastasia!

May 03, 2021   Our paper describing a fluorescence lifetime-based approach for quantitative and multiplexed imaging of intercellular tensile forces has been accepted by Angew Chem Int EdThis paper has also been selected as a Very Important Paper (VIP).

April 30, 2021   Mingxu has been selected as a Camille Dreyfus Teacher-ScholarFor more information, please check this UMass NewsThanks, the Camille & Henry Dreyfus Foundation!

April 06, 2021   Dr. Kewei Ren has accepted an offer from Nanjing University of Science and Technology in China.  He will be a Professor of Chemical Engineering and starts his own lab!  Congrats, Kewei!

March 30, 2021   Our invited review describing recent development of genetically encoded RNA nanodevices that can be used for cellular imaging and regulation has been accepted by Nanoscale in a special issue of Emerging Investigators.

March 29, 2021   Mingxu joins the editorial board of Biosensors, new submissions are welcome!

February 22, 2021   Chemistry major graduate students, Lan Mi and Zhaolin Xue, join our lab.  Welcome Lan and Zhaolin!

February 16, 2021   Biochemistry major undergrad, Jahn Pothier, joins the lab.  Welcome!

2020

December 28, 2020   Our paper describing lipid-DNA conjugate-based efficient and selective membrane modification on various bacterial cells has been accepted by Chemical Science.

December 04, 2020   Yousef Bagheri receives the Paul Hatheway Terry Scholarship in recognition of his research and academic standing.  Congrats, Yousef!

December 03, 2020   A special issue of DNA Nanotechnology on Bio-membranes edited by Prof. Mingxu You and Dr. Bin Zhao is now accepting original research and review papers!

October 16, 2020   Our invited review paper describing current methods for measuring cell membrane transient interactions has been accepted by Front Chem in a special issue of Rising Stars.

August 18, 2020   Puspam Keshri is awarded William E McEwen Fellowship Award for outstanding poster presentation during ResearchFest 2020.  Congrats, Puspam!

August 14, 2020   Our paper describing an RNA aptamer-based photosensitizer for targeted cell regulation has been accepted by Angew Chem Int Ed.

July 22, 2020   Our paper describing a DNA-based probe to quantify intercellular tensile forces has been accepted by Chemical Science.

July 09, 2020   Mingxu joins the editorial board of Membranes, new submissions are welcome!

June 08, 2020   The lab reopens following a COVID-19 shut down in March.

May 06, 2020   Our invited paper describing the first fluorogenic RNA sensors in a paper substrate for the point-of-care testing has been accepted by Anal Methods in a special issue of Emerging Investigators.

April 20, 2020   Manojkumar Narayanan, passes his M.S. thesis defense from UMass Lowell biology program.  Congrats, Manoj!

February 07, 2020   Our invited paper describing live-cell dynamic imaging of small molecules using ratiometric RNA-based sensors has been accepted by ACS Applied Bio Materials.

January 22, 2020   Our paper describing a genetically encoded RNA hybridization chain reaction for imaging RNA sub-cellular locations has been accepted by JACS.

January 21, 2020   Chemistry major undergrad, Zhixin Mo, and Honor college student, Alan Chai, join the lab.  Welcome!

2019

December 17, 2019   Chemistry major graduate students, Ru Zheng and Ahsan Ausaf Ali, join our lab.  Welcome Ahsan and Ru!

November 26, 2019   Yousef Bagheri receives a Biophysical Society travel award to attend 2020 Biophysical Society Annual Meeting.  Congrats, Yousef!

November 18, 2019   Our invited review paper describing the process and application of lipid-oligonucleotide conjugates for cell membrane engineering and analysis has been accepted by Current Opinion in Biomedical Engineering.

November 12, 2019   Prof. Yang Shu from Northeastern University of China joins the lab as a visiting scholar.  Welcome, Yang!

October 23, 2019   Our paper describing a comprehensive quantification of the dynamic modification process of lipid-DNA probes onto live cell membranes has been accepted by Chemical ScienceThis paper has been selected as a 2019 Chemical Science HOT Article.

October 11, 2019   Nuanfei Zhu from Jiangsu University joins the lab as a visiting graduate student.  Welcome, Nuanfei!

October 07, 2019   Our paper describing the quantitative imaging of small molecules using ratiometric RNA-based sensors has been accepted by Angew Chem Int Ed.

September 13, 2019   Chemistry major undergrad, Jikun Wang, Biochemistry major undergrads, Yiwen Xie, Zachary Gentile, Saoirse Connolly, and David Lutati, join the lab.  Welcome!

August 27, 2019   A five-year NIH grant!  We are honored to receive a Maximizing Investigators’ Research Award (MIRA R35). For more information, please check this UMass NewsThanks, NIGMS!

August 27, 2019   Qikun Yu and Rigumula Wu are both awarded William E McEwen Fellowship Awards for outstanding poster presentation during ResearchFest 2019.  Congrats, Rigumula and Qikun!

June 07, 2019   Our invited review paper describing lipid-DNA conjugates for cell membrane modification, analysis, and regulation has been accepted by Supramol Chem in a special issue of Emerging Supramolecular Chemists in North America.

May 28, 2019   CURE-REU undergrad student from UT Austin, Nicholas Fong, joins the lab for summer research.  Welcome, Nicholas!

May 28, 2019   UMass Lowell biology graduate student, Manojkumar Narayanan, joins the lab for the M.S. thesis research.  Welcome, Manojukumar!

May 28, 2019   Our collaborative paper describing a DNA-based microfluidic device for potassium detection during dialysis treatment has been accepted by Biomed Eng OnLine.

April 26, 2019   Mark Leon-Duque has received a Mr. Tompkins Award, an Edward Shapiro Fund Award, and an ACS-Connecticut Valley Section Student Award.  Congrats, Mark!

April 26, 2019   Sara Chedid has received an Oliver Zajicek Memorial Scholarship Award and a Chemistry Departmental Recognition Award.  Congrats, Sara!

April 16, 2019   A seed fund from IALS M2M is awarded to support our collaboration with Prof. Anne Gershenson at UMass.  Thanks, M2M!

March 27, 2019   Qikun Yu receives a CBI travel grant.  Congrats, Qikun!

March 23, 2019   Yousef Bagheri and Qikun Yu receive the department travel grant for graduate students.  Congrats, Yousef and Qikun!

March 18, 2019   Yousef Bagheri receives a funding to attend a week-long Quantitative Fluorescence Microscopy course at MDI Biological Laboratory in Maine.  Thanks, M2M and Light Microscopy Facility!

February 19, 2019   Mingxu has been selected as a Sloan Research Fellow in chemistry.  For more information, please check this UMass News Thanks, Alfred P. Sloan Foundation!

February 05, 2019   We have received a five-year NSF CAREER Award to support our development of genetically encoded RNA-based sensors.  For more information, please check this UMass NewsThanks, CBET!

February 05, 2019   Our invited review paper describing intracellular imaging with genetically encoded RNA-based sensors has been accepted by Nanomaterials.

January 22, 2019   Biochemistry major freshman, Rafael De Pillis, joins the lab.  Welcome, Rafael!

January 15, 2019   Mingxu joins the editorial board of PeerJ Analytical Chemistry, new submissions are now welcome!

January 13, 2019   Our invited review paper describing recent advancement of fluorogenic RNA-based sensors has been accepted by Methods.

2018

December 17, 2018   Our paper describing an RNA integrator sensor for intracellular imaging of low-abundance metabolites has been accepted by Cell Chem Biol.

December 13, 2018   Our paper describing a genetically encoded RNA-based sensor for intracellular imaging of silver ions has been accepted by ChemComm.

December 06, 2018   Chemistry major graduate student, Qian Tian, joins our lab.  Welcome Qian (Tina)!

October 29, 2018   Mark Leon-Duque, undergrad in the lab, has been awarded the 2018-2019 UMass Amherst Rising Researcher Student Achievement Award.  Congrats, Mark!

September 05, 2018   Biochemistry major undergrad, Tony Nguyen, joins the lab.  Welcome, Tony!

August 29, 2018   Yousef is awarded William E McEwen Fellowship Award for outstanding poster presentation during ResearchFest 2018.  Congrats, Yousef!

August 21-22, 2018   Mingxu organizes a two-day “super” symposium on “Nucleic Acid-based Sensors” at the 256th ACS National Meeting.  He also gives two invited talks on intercellular force sensors and genetically encoded RNA sensors, respectively.  Thanks for the support from a wonderful group of speakers in the symposium!

August 17, 2018   Chemistry major graduate student, Puspam Keshri, joins our lab.  Welcome Puspam!

July 30, 2018   Kewei Ren joins the lab as a postdoctoral research associate.  Welcome Kewei!

June 26, 2018   Our paper describing a novel genetically encoded RNA circuit for low-abundance RNA imaging has been accepted by JACS.

March 14, 2018   Casey O’Brien, undergrad in the lab, has been awarded the Richard W. Fessenden Excellence Award for two graduating seniors, and the Departmental Recognition Award for two outstanding chemistry majors any years.  Congrats, Casey!

March 14, 2018   Undergrad in the lab, Katherine Poisson, has been awarded an American Institute of Chemists Award for a senior chemistry major who has demonstrated an outstanding record of achievement, leadership and character, and was also recognized as a Distinguished Undergraduate TA.  Congrats, Kate!

March 14, 2018   Mark Leon-Duque, undergrad in the lab, has been awarded the 2018 Richason Award for being a rising senior dedicated to academics and strong character, and a Bradspies Summer Research Fellowship.  Congrats, Mark!

February 28, 2018   Our collaboration paper describing an isothermal method to exponentially amplify DNA has been published in Chemical Science.

February 13, 2018   Our collaborative NIH R01 grant with Prof. Stephen Lory at Harvard Medical School and X-Chem, LLC has been awarded.  Thanks, NIAID!

February 06, 2018   Biochemistry major undergrad, Kathleen McAuliffe, chemistry major undergrad, Rashad Almadani, together with a chemistry major undergrad from Mount Holyoke College, Yeonsoo Kum, join the lab.  Welcome!

2017

December 15, 2017   Chemistry major graduate student, Zhining (Jennings) Sun, joins our lab.  Welcome Jennings!

December 06, 2017   Our paper describing a novel DNA probe for intercellular tensile force measurement has been accepted by JACS.

June 06, 2017   Qikun Yu, graduate student in the lab, is awarded 2-year UMass Chemistry-Biology Interface Traineeship.  Congrats, Qikun!

April 21, 2017   Mark Leon-Duque, undergrad in the lab, was awarded the Uche Anyanwu Memorial Award for Outstanding Research.  Congrats, Mark!

April 10, 2017   A seed fund from IALS M2M is awarded to support our collaboration with Prof. Yubing Sun at UMass.  Thanks, M2M!

April 03, 2017   Undergrad in the lab, Casey O’Brien, has been awarded the Bradspies Summer Research Fellowship.  Congrats, Casey!

February 02, 2017   Chemistry major graduate student, Yousef Bagheri, joins our lab.  Welcome Yousef!

January 23, 2017   Four chemistry major undergraduate students, Mark Leon-Duque, Sara Chedid, Casey O’Brien, and Katherine Poisson, together with one microbiology major junior, Alden Richter, join the lab.  Welcome!!

2016

December 16, 2016   Chemistry major graduate students, Rigumula Wu and Qikun Yu, officially join our lab.  Welcome Rigumula!  Welcome Qikun! 

November 25, 2016   Our paper describing a novel DNA probe for monitoring dynamic lipid encounters on live cell membranes has been accepted by Nature Nanotechnology.

November 14, 2016   Jing Shi from Tsinghua University joins the lab as a visiting student.  Welcome Jing!

November 14, 2016   Bin Zhao joins the lab as a postdoctoral research associate.  Welcome Bin! 

October 02, 2016   Aruni Karunanyake joins the lab as a research fellow.  Welcome Aruni!

September 2016   Mingxu becomes faculty member of Institute for Applied Life Sciences,  Chemistry-Biology Interface Program, Molecular & Cellular Biology Graduate Program,  Center for Biological Physics, and Center for Clinical and Translational Science at UMass Amherst.

August 29, 2016   Day 1 of the You Lab at UMass Amherst!

June 02, 2016   Our collaboration paper describing an ultrafast excited state proton transfer of fluorinated GFP chromophore has been accepted by Chemical Science.

April 19, 2016   Our paper describing how to design and optimize fluorogenic riboswitch sensors has been published in Methods in Enzymology.

March 24, 2016   The You Lab website is now up and running!  Welcome!