Publications at UMass

[14]  Y. Bagheri#, A. A. Ali#, P. Keshri, J. Chambers, A. Gershenson*, & M. You*. (2022) “Imaging membrane order and dynamic interactions in living cells with a DNA Zipper probe”. Angew Chem Int Ed, 61, e202112033.

[13]  Z. Sun, R. Wu, B. Zhao, P. Chien*, & M. You*. (2021) “Live-cell imaging of guanosine tetra- and pentaphosphate (p)ppGpp with RNA-based fluorescent sensors”.  Angew Chem Int Ed, 60, 24040-24047.

[12]  P. Keshri#, B. Zhao#*, T. Xie, Y. Bagheri, J. Chambers, Y. Sun, & M. You*. (2021) “Quantitative and multiplexed fluorescence lifetime imaging of intercellular tensile forces”.  Angew Chem Int Ed, 60, 15548-15555.  [recognized as a Very Important Paper]

[11]  Q. Tian, Y. Bagheri, P. Keshri, R. Wu, K. Ren, Q. Yu, B. Zhao, & M. You*. (2021) “Efficient and selective DNA modification on bacterial membranes”.  Chem Sci, 12, 2629-2634.

[10]  K. Ren, P. Keshri, R. Wu, Z. Sun, Q. Yu, Q. Tian, B. Zhao, Y. Bagheri, Y. Xie^, & M. You*. (2020) “A genetically encoded RNA photosensitizer for targeted cell regulation”.  Angew Chem Int Ed, 59, 218986-21990.

[9]   B. Zhao, N. Li, T. Xie, Y. Bagheri, C. Liang, P. Keshri, Y. Sun*, & M. You*. (2020) “Quantifying tensile forces at cell-cell junctions with a DNA-based fluorescent probe”.  Chem Sci, 11, 8558-8566.

[8]   K. Ren, R. Wu, A.P.K.K. Karunanayake Mudiyanselage, Q. Yu, B. Zhao, Y. Xie^, Y. Bagheri, Q. Tian, & M. You*. (2020) “In situ genetically cascaded amplification for imaging RNA subcellular locations”.  J Am Chem Soc, 142, 2968-2974.

[7]   Y. Bagheri, S. Chedid^, F. Shafiei, B. Zhao*, & M. You*. (2019) “Quantitative assessment of the dynamic modification of lipid-DNA probes on live cell membranes”.  Chem Sci, 10, 11030-11040.   [2019 Chemical Science HOT Article]

[6]   R. Wu, A.P.K.K. Karunanayake Mudiyanselage, F. Shafiei, B. Zhao, Y. Bagheri, Q. Yu, K. McAuliffe^, K. Ren, & M. You*. (2019) “Genetically encoded ratiometric RNA-based sensors for quantitative imaging of small molecules in living cells”.  Angew Chem Int Ed, 58, 18271-18275.

[5]   M. You*, J.L. Litke, R. Wu, & S.R. Jaffrey*. (2019) “Detection of low-abundance metabolites in live cells using an RNA integrator”.  Cell Chem Biol, 26, 471-481.   [See also Cell Chem Biol Preview]

[4]   Q. Yu#, J. Shi#, A.P.K.K. Karunanayake Mudiyanselage, R. Wu, B. Zhao, M. Zhou* & M. You*. (2019) “Genetically encoded RNA sensors for intracellular imaging of silver ions”.  Chem Commun, 55, 707-710.

[3]   A.P.K.K. Karunanayake Mudiyanselage, Q. Yu, M.A. Leon-Duque^, B. Zhao, R. Wu & M. You*. (2018) “Genetically encoded catalytic hairpin assembly for sensitive RNA imaging in live cells”.  J Am Chem Soc, 140, 8739-8745.

[2]   B. Zhao, C. O’Brien^, A.P.K.K. Karunanayake Mudiyanselage, N. Li, Y. Bagheri, R. Wu, Y. Sun & M. You*. (2017) “Visualizing intercellular tensile forces by DNA-based membrane molecular probes”.  J Am Chem Soc, 139, 18182-18185.

[1]   M. You#*, Y. Lyu#, D. Han#, L. Qiu, Q. Liu, T. Chen, C. Wu, L. Peng, L. Zhang, G. Bao & W. Tan*. (2017) “DNA probes for monitoring dynamic and transient molecular encounters on live cell membranes”.  Nature Nanotechnology, 12, 453-459.   [See also Nat Nano News and Views, Hunan University NewsSina News, Sohu News, NSFC News]

Prior Publications

[12]  D. Han#, C. Wu#, M. You#, T. Zhang, T. Chen, L. Qiu, Z. Zheng & W. Tan. (2015) “A cascade reaction network mimicking the basic functional steps of acquired immune response”. Nature Chemistry, 7, 835-841. (# Co-first author)

[11]  M. You#, J.L. Litke# & S.R. Jaffrey. (2015) “Imaging metabolite dynamics in living cells using a spinach-based riboswitch”. Proc Natl Acad Sci USA, 112, E2756-E2765. (# Co-first author) [Highlighted by Nature Biotechnology]

[10]  M. You, G. Zhu, M. Altman, J. Wang, T. Chen, M.J. Donovan & W. Tan. (2015) “Programmable and multi parameter DNA-based logic platform for cancer recognition and targeted therapy”. J Am Chem Soc, 137, 667-674. [ACS editor’s choice; Cover story]

[9]   L. Peng, M. You, C. Wu, D. Han, I. Ocsoy, T. Chen, Z. Chen & W. Tan. (2014) “Reversible phase transfer of nanoparticles based on photoswitchable host-guest chemistry”. ACS Nano, 8, 2555-2561.

[8]   M. You, L. Peng, N. Shao, L. Zhang, L. Qiu, C. Cui & W. Tan. (2014) “DNA ‘nano-claw’: logic-based autonomous cancer targeting and therapy”. J Am Chem Soc, 136, 1256-1259.

[7]   F. Huang, M. You, D. Han, H. Liang & W. Tan. (2013) “DNA branch migration reactions through photo-controllable toehold formation”. J Am Chem Soc, 135, 7967-7973.

[6]   M. You, Y. Chen, X. Zhang, H. Liu, R. Wang, K.R. Williams & W. Tan. (2012) “An autonomous and controllable light-driven DNA walking device”. Angew Chem Int Ed, 51, 2457-2460. [Inside back cover; Highlighted by news (2012) DNA walker strides towards the light. Chemistry World of Royal Chemical Society]

[5]   M. You, F. Huang, Z. Chen, R. Wang & W. Tan. (2012) “Building a nanostructure with reversible motions using photonic energy”. ACS Nano, 6, 7935-7941. [Highlighted by perspective (2012) Racing with nature: artificial nanomachines that keep running on light, both left and right. ACS Nano 6, 7553-7555; Highlighted by news (2012) Photoisomerization drives nanowalker. C & EN, 32, 36]

[4]   L. Peng, M. You, Q. Yuan, C. Wu, D. Han, Y. Chen, Z. Zhong, J. Xue & W. Tan. (2012) “Macroscopic volume change of dynamic hydrogels induced by reversible DNA hybridization”. J Am Chem Soc, 134, 12302-12307.

[3]   M. You, R. Wang, X. Zhang, Y. Chen, K. Wang & W. Tan. (2011) “Photon-regulated DNA-enzymatic nanostructures by molecular assembly”. ACS Nano, 5, 10090-10095.

[2]   K. Wang, M. You, Y. Chen, D. Han, Z. Zhu, J. Huang, K.R. Williams & W. Tan. (2011) “Self-assembly of a bifunctional DNA carrier for drug delivery”. Angew Chem Int Ed, 50, 6098-6101.

[1]   M. You, Z. Zhu, H. Liu, B. Gulbakan, D. Han, R. Wang, K.R. Williams & W. Tan. (2010) “Pyrene-assisted efficient photolysis of disulfide bonds in DNA-based molecular engineering”. ACS Appl Mater Interfaces, 2, 3601-3605.