Target Protein Degradation

296)

Dutta, R.*; Alp, Y.*; Gupta, P.*; Singh, B.*, & Thayumanavan, S. “Multivalent Ligand-Protein Interactions Using Polymeric Lysosome-Targeting Chimeras (PolyTACs) Leads to Lysosome-Targeting Receptor-Independent Degradation of Transmembrane Proteins.” bioRxiv, 2025-05.

 

295)
Dutta, R. *; Devarajan, A.*; Talluri, A.; Das, R.; and Thayumanavan, S.; “Dual-Action-Only PROTACs” Journal of the American Chemical Society, 2025(10.1021/jacs.5c00131)
Figure 1
292)

Lu, H.H.*; Krishna, J*; Alp, Y; Thayumanavan S.” Polymeric Lysosomal-Targeting Chimeras: Extracellular Targeted Protein Degradation Without Co-opting Lysosome-Targeting Receptors” BioRxiv, (https://doi.org/10.1101/2024.09.18.613672)