Targeted Delivery


Kanjilal, P.; Singh, K.; Das, R.; Matte, J. and Thayumanavan, S. “Antibody Polymer Conjugates (APCs) for Active Targeted Therapeutic Delivery” Biomacromolecules 2023, 24, 8, 3638–3646, (DOI:10.1021/acs.biomac.3c00385)


Wu, P.; Prachyathipsakul, T.; Huynh, U.; Qiu, J.; Jerry, D. J. and Thayumanavan, S. “Optimizing Conjugation Chemistry, Antibody Conjugation Site, and Surface Density in Antibody–Nanogel Conjugates (ANCs) for Cell-Specific Drug Delivery” Bioconjugate Chem. 2023, 34, 4, 707-718, (DOI:10.1021/acs.bioconjchem.3c00034)


Huynh, U.; Wu, P.; Qiu, J.; Prachyathipsakul, T.; Singh, K.; Jerry, D.J.; Gao, J. and Thayumanavan, S. “Targeted Drug Delivery Using a Plug-to-Direct Antibody–Nanogel Conjugate” Biomacromolecules 2023, 24, 849−857, (DOI:10.1021/acs.biomac.2c01269)


Dutta, K.; Das, R.; Medeiros, J.; Kanjilal, K.; Thayumanavan, S.“Charge-Conversion Strategies for Nucleic Acid Delivery” Adv. Funct. Mater., 2021, 31, 2011103. (DOI:10.1002/adfm.202011103)


Liu, B.; Singh, K.; Gong, S.; Canakci, M.; Osborne, B.A.; Thayumanavan, S. “Protein-Antibody Conjugates (PACs): A Plug-and-Play Strategy for Covalent Conjugation and Targeted Intracellular Delivery of Pristine Proteins” Angew. Chemie. Int. Ed., 2021 , 60, 12813-12818 . (DOI:10.1002/anie.202103106)


Dutta, K.; Das, R.; Medeiros, J. M.; Thayumanavan, S. “”Disulfide Bridging Strategies in Viral and Non-viral Platforms for Nucleic Acid Delivery” Biochemistry, 2021, 60, 13, 966–990. (DOI:10.1021/acs.biochem.0c00860)


Gao, J.; Dutta, K.; Zhuang, J.; Thayumanavan, S. “Cellular and subcellular targeted delivery using a simple all-in-one polymeric nanoassembly” Angew. Chem. Int. Ed., 2020, 59, 23466-23470 . (DOI: 10.1002/anie.202008272)